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Alex Palazzo is a postdoctoral fellow working in the Department of Cell Biology at Harvard Medical School.
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November 30, 2006
Rich Jorgensen on the RNAi Nobel.
Category: Pure Biology
Rich Jorgensen on the RNAi Nobel.
Posted by Alex Palazzo at 9:23 AM • 2 Comments • 0 TrackBacks
November 29, 2006
RNA + Body Fluids (the results are in)
Category: Pure Biology
I finally did the experiment ... and more. Come see the results.
Posted by Alex Palazzo at 5:20 PM • 18 Comments • 0 TrackBacks
Proks have dynamin like molecules!
Category: Pure Biology
When I was a grad student, eukaryotes had all the neatest toys ... actin, microtubules, kinesins, dynein, myosin, dynamin, SNAREs ... OK that's not totally true - bacteria had their version of tubulin (the constituent of microtubules), and it's...
Posted by Alex Palazzo at 10:18 AM • 7 Comments • 0 TrackBacks
November 27, 2006
Neil deGrasse Tyson & Richard Dawkins
Category: Science & Society
I mostly agree with Tyson ... [Here's a different take on the whole culture-war phenomenon, what we scientists need to fight aggressively for is tolerance ... tolerance for ATHEISTS. On this front Dawkins is losing ground.] [HT: Ed Brayton]...
Posted by Alex Palazzo at 10:26 PM • 4 Comments • 0 TrackBacks
This pisses me off
Category: Science & Society
An OpEd in today's NY Times about "the story of the Enlightenment that may be more illusory than real". WTF?
Posted by Alex Palazzo at 9:41 AM • 2 Comments • 0 TrackBacks
November 26, 2006
NEXTgencode
Category: Misc
Want a permapuppy? How about increased BLSHt expression? Or a larger ear? Now there's a company for you!
Posted by Alex Palazzo at 3:17 PM • 5 Comments • 0 TrackBacks
Thanksgiving
Category: Lab Life
Thursday, my wife and I hosted our annual Thanksgiving for the left behind. Every year, we gather all the foreigners and Americans who couldn't make it back to their own family and have a great big feast. This year, we...
Posted by Alex Palazzo at 9:25 AM • 0 Comments • 0 TrackBacks
November 24, 2006
Map that Campus XXIV
Category: Map that Campus
Thanksgiving edition!
Posted by Alex Palazzo at 10:05 AM • 6 Comments • 0 TrackBacks
November 23, 2006
Note added in proof
Category: Misc
If you haven't seen this, Orac is shocked that I'm shocked and then proceeds to give a run down of other autism related quackery ... go check it out. In contrast, Abel Pharmboy is joyous about my shockingly shocked post....
Posted by Alex Palazzo at 9:21 AM • 1 Comments • 0 TrackBacks
November 21, 2006
Autism & RNA????
Category: Science & Society
Autism seems to keep popping up everywhere. In today's NYTimes there's an commentary on new Federal legislation whose aim is to boost Autism research. But that's not what I want to talk about. So I've been perusing a couple of...
Posted by Alex Palazzo at 4:01 PM • 45 Comments • 0 TrackBacks
November 20, 2006
McGill Radio & Access to Essential Medicines
Category: Science & Society
So not only is McGill's radio station CKUT hosting a new show on global health, Health on Earth, but for their first edition they'll be talking about the Access to Essential Medicines campaign spearheaded by Doctors Without Borders. You may...
Posted by Alex Palazzo at 8:35 PM • 1 Comments • 0 TrackBacks
The latest on the Tonegawa incident
Category: Lab Life
It looks like Tonegawa stepped down as head of MIT's Picower Institute after the kerfuffle over his emails to Alla Karpova, who was offered a job at MIT's McGovern Institute. Read the article in today's Boston Globe: MIT neuroscience center...
Posted by Alex Palazzo at 12:33 PM • 0 Comments • 0 TrackBacks
N=3
Category: Science & Society
The Gold Standard for some experimentalists. Here's a video of a dog and a blender that vividly demonstrates this concept.
Posted by Alex Palazzo at 10:15 AM • 3 Comments • 0 TrackBacks
Are they really intronless?
Category: Pure Biology
I've been doing some digging with respect to the survey of intronless genes that I wrote about yesterday ...
Posted by Alex Palazzo at 8:22 AM • 5 Comments • 0 TrackBacks
November 19, 2006
Intronless Genes
Category: Pure Biology
Ask most biologists and they'll tell you that in "higher eukaryotes" all genes have introns. But that's not quite true. Here are some stats from the SEGE (Single Exonic Genes in Eukaryotes) website:
Posted by Alex Palazzo at 4:15 PM • 7 Comments • 0 TrackBacks
Academics in Iraq
Category: Science & Society
You've probably heard this, but earlier this week many individuals (Shiites, Sunni Arabs, and Sunni Kurds) affiliated with Iraq's small academia were rounded up by gunmen. From the Boston Globe: On Tuesday, gunmen dressed like Interior Ministry commandos abducted as...
Posted by Alex Palazzo at 11:07 AM • 0 Comments • 0 TrackBacks
November 17, 2006
A Subclass of mRNAs Use a Different Nuclear Export Machine
Category: Pure Biology
From the latest JCB: mRNAs that encode proteins responsible for cell cycle regulation, use their own export machinery.
Posted by Alex Palazzo at 9:20 AM • 1 Comments • 0 TrackBacks
Map that Campus XXIII
Category: Map that Campus
#23 has quite a following. There's a movie comming out and yes it's the 23rd edition of Map that Campus.
Posted by Alex Palazzo at 8:32 AM • 9 Comments • 0 TrackBacks
November 16, 2006
Eating Lipids to Fuse Mitos
Category: Pure Biology
So the latest piece of the puzzle came in ... I just saw a paper in the latest Nature Cell Biology on how a version of phospholipaseD acts to promote membrane fusion of the outer mitochondrial membrane.
Posted by Alex Palazzo at 4:53 PM • 0 Comments • 0 TrackBacks
November 15, 2006
Anne-Sophie Mutter
Category: art, food, music, citylife and other mental stimuli
... is a force of nature. At times you get the impression that she wields her bow like a sword, dripping from the blood of the piece she just slayed. Last night we saw her ...
Posted by Alex Palazzo at 6:37 PM • 2 Comments • 0 TrackBacks
Students Across North America Call for Universities to Stop Abetting Access-to-Medicines Crisis in Poor Countries
Category: Science & Society
Chapters of Universities Allied for Essential Medicines (UAEM) are pushing their local universities to sign Equitable Access Licenses (EAL) that would lift patent barriers on drugs developed by university labs. These agreements would effectively increase the access of medicines...
Posted by Alex Palazzo at 3:09 PM • 5 Comments • 0 TrackBacks
November 14, 2006
Focal Adhesions and Cell Motility
Category: Pure Biology
This is for cell motility aficionados. How do cells crawl? Well most in the field would say that actin polymerization generated by the Arp2/3 complex at the leading edge acts to generate an actin meshwork (see pic). The addition...
Posted by Alex Palazzo at 6:36 PM • 3 Comments • 0 TrackBacks
November 13, 2006
Talking in X-speak
Category: Lab Life
Working in a lab for too long and you'll acquire a type of lingo that we call "X-speak". It happens to everyone you borrow words used within one environment and apply them to other situations. With so many members of...
Posted by Alex Palazzo at 11:20 AM • 7 Comments • 0 TrackBacks
November 10, 2006
Map that Campus XXII
Category: Map that Campus
It's that time of the week. Let's try something a bit more challenging. Here is today's mystery campus: Hint: How proteins get into these organelles. Leave your answers in the comment section....
Posted by Alex Palazzo at 8:48 AM • 15 Comments • 0 TrackBacks
November 9, 2006
Quote of the day
Category: Lab Life
Ever tried. Ever failed. No matter. Try Again. Fail again. Fail better."-Samuel Beckett...
Posted by Alex Palazzo at 3:35 PM • 6 Comments • 0 TrackBacks
My two cents on the election
Category: Misc
... while I'm waiting for our daily lunch caravan to assemble. My 10 sec analysis: - A partial change in governance will be good for the country. Hopefully funding will increase for education and science. - Look at these maps...
Posted by Alex Palazzo at 12:31 PM • 0 Comments • 0 TrackBacks
November 7, 2006
And the best political ad of this campaign season is ...
Category: Misc
Not only funny, but reminds the voting population that we must disregard these ridiculous attack ads....
Posted by Alex Palazzo at 8:58 AM • 2 Comments • 0 TrackBacks
November 6, 2006
Editorial in Today's NY Times on College Sports
Category: Education
One thing I never understood about US colleges is the amount of money pumped into their sports teams. It's an open invitation to wasted resources and (in worse case scenarios) corruption. From today's NY Times:...
Posted by Alex Palazzo at 6:19 PM • 3 Comments • 0 TrackBacks
How Doa10p gets into the nucleus, or another freaky experiment done in yeast
Category: Pure Biology
A paper on 1) protein degradation in the nucleus, 2) how membrane bound proteins cross the NPC, and 3) crazy experiments you can perform in yeast.
Posted by Alex Palazzo at 3:33 PM • 0 Comments • 0 TrackBacks
November 5, 2006
Pre-election media tid-bits
Category: Misc
A collection of interesting bits of info.
Posted by Alex Palazzo at 12:22 PM • 0 Comments • 0 TrackBacks
November 4, 2006
Saturday Morning Video
Category: art, food, music, citylife and other mental stimuli
Well, last week we had Frank Zappa comment on the state of the media, now let's hear what Thom Yorke has to say about the political process: And if you want to sing along:...
Posted by Alex Palazzo at 8:33 AM • 1 Comments • 0 TrackBacks
November 3, 2006
More on the Tonegawa Saga
Category: Lab Life
I didn't blog about this when it first came out, go see Janet Stemwedel's blog (here, here and here) on how Susumu Tonegawa dissuaded Alla Karpova from taking a position at MIT. Here's the latest from the Boston Globe:...
Posted by Alex Palazzo at 9:45 AM • 0 Comments • 0 TrackBacks
Map that Campus XXI
Category: Map that Campus
I guess last week's mystery campus was way too easy, congrats to Arrowsmith for his two correct answers. This week will be a little harder. So here is this week's "campus": hint: Great place to have a trip, I got...
Posted by Alex Palazzo at 8:31 AM • 9 Comments • 0 TrackBacks
The cost of Iraq
Category: Science & Society
How much is this botched war costing us? From the National Priorities Project, who base their data on congressional appropriations, the up-to-the-minute total is $339 billion. As for 2006, the current estimate is $100.4 billion. From zfacts: The US budget...
Posted by Alex Palazzo at 8:22 AM • 0 Comments • 0 TrackBacks
November 2, 2006
I love this site
Category: Lab Life
I know that we have NCBI etc. but couldn't someone construct something close to the Yeast Genome Data Base for the human genome??? This site rocks. (P.S. Yes probably ENSEMBL is the best pan genome bioinformatics gateway, I'm exploring it...
Posted by Alex Palazzo at 9:43 AM • 3 Comments • 0 TrackBacks
