Alex Palazzo is a postdoctoral fellow working in the Department of Cell Biology at Harvard Medical School.
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December 31, 2006
Category: art, food, music, citylife and other mental stimuli
(This is back dated as I would like to start the new year on a brighter note.) After a long day of skiing in the green hills of Vermont, my brother , cousin and I decided to go for a...
Posted by Alex Palazzo at 11:59 PM • 2 Comments •
December 29, 2006
Category: Map that Campus
Last one for this year.
Posted by Alex Palazzo at 10:52 AM • 13 Comments •
December 28, 2006
Category: art, food, music, citylife and other mental stimuli
(I wish) I though I could spend a day or too relaxing ... but it seems like I can't do it. Today was spent cleaning the apartment in preparation for a family visit down from Montreal. We're actually meeting up...
Posted by Alex Palazzo at 2:36 PM • 1 Comments •
December 27, 2006
Category: Pure Biology
2006 was (again) year of the RNA. Two nobels. The RNA world expanded with the discovery of Piwi RNA. RNAi as a transmittable trait? (Lamarck is vindicated!) We also found out that much of the conserved parts of our genome...
Posted by Alex Palazzo at 9:13 AM • 5 Comments •
December 26, 2006
Category: art, food, music, citylife and other mental stimuli
Posted by Alex Palazzo at 8:16 AM • 4 Comments •
December 24, 2006
Category: Pure Biology
Check this out: First-in-Human Experience of an Antidote-Controlled Anticoagulant Using RNA Aptamer Technology From the paper:...
Posted by Alex Palazzo at 8:12 AM • 5 Comments •
December 23, 2006
Category: Science & Society
... I was listening to NPR where they were discussing the bonus that Goldman Sachs gave to its CEO, Lloyd C. Blankfein, a record of $53.4 Million. Some one called to say...
Posted by Alex Palazzo at 12:10 PM • 1 Comments •
Category: Pure Biology
Earlier this week you probably read the whole saga of how researchers tracked down some individuals who could not sense pain. They then identified the gene responsible as SCN9A, a voltage-gated sodium channel and that was published in Nature. But...
Posted by Alex Palazzo at 11:29 AM • 2 Comments •
December 20, 2006
Category: Misc
Chris Phoenix asked me to comment on his entry: Studying Molecular Biology. As someone who is constantly playing around with cells I'll add this advice to how biological systems differ from watches and the Antikythera Mechanism, biological systems are composed...
Posted by Alex Palazzo at 8:45 AM • 0 Comments •
December 19, 2006
Category: art, food, music, citylife and other mental stimuli
Last week was too stressful - although by Friday afternoon I had put together the pieces of the puzzle and it all makes sense (I'd tell you more about it, potentially I've stumbled upon a really cool little "cellular circuit",...
Posted by Alex Palazzo at 2:26 PM • 0 Comments •
December 15, 2006
Category: Map that Campus
Another week, another mystery campus ...
Posted by Alex Palazzo at 9:50 AM • 8 Comments •
December 14, 2006
Category: art, food, music, citylife and other mental stimuli
From Kazuo Ishiguro's Never Let Me Go.
Posted by Alex Palazzo at 8:37 AM • 3 Comments •
December 13, 2006
Category: Lab Life
Here's a happiness scale for you. Add your own lab experiences with the appropriate number.
Posted by Alex Palazzo at 4:37 PM • 14 Comments •
Category: Science & Society
Check out the video here. [HT: kscs]...
Posted by Alex Palazzo at 8:29 AM • 2 Comments •
Category: Lab Life
Time for a therapy session. Man I hate this. My cortisol levels must be through the roof. I tested my clones and got weird results. I was racking my brain all weekend trying to figure out why. Then yesterday I...
Posted by Alex Palazzo at 8:13 AM • 2 Comments •
December 12, 2006
Category: Pure Biology
Apparently weak and strong signal sequences are differentially targeted to the ER acording to a new paper in Cell.
Posted by Alex Palazzo at 8:55 AM • 4 Comments •
December 9, 2006
Category: Misc
Baltimore on Dawkins. Three kingdoms? Skeptical publishing. Integrins & migration. Libertarians & adolescents? Kant vs. Archimedes. Yes they're all below the fold.
Posted by Alex Palazzo at 8:14 AM • 4 Comments •
December 8, 2006
Category: Pure Biology
Yesterday Melissa Moore gave a talk at the School of Public Health here at Harvard Med School. She had lots of data - on nonsense mediated decay (how cells degrade mRNA transcripts with premature stop codons that arise through various...
Posted by Alex Palazzo at 8:13 PM • 4 Comments •
Category: Map that Campus
It's that time again. Here is this week's mystery campus: hint: fatal element. As usual, leave your answers in the comment section....
Posted by Alex Palazzo at 11:02 AM • 8 Comments •
December 7, 2006
Category: Lab Life
... is with me. Two constructs to make. Two colonies I had. Each trial a single clone. I cut them, they cut just the way I hoped. Each clone was sequenced. The sequence told me that I have what I...
Posted by Alex Palazzo at 8:48 AM • 2 Comments •
December 6, 2006
Category: Pure Biology
Wow, this is how the machine works!
Posted by Alex Palazzo at 10:20 AM • 7 Comments •
Category: Science & Society
From today's Boston Globe: Harvard has whittled down hundreds of nominees for its next president to a small list, including internal candidates and presidents of some of the nation's top universities, according to a source familiar with the process. The...
Posted by Alex Palazzo at 8:35 AM • 3 Comments •
December 4, 2006
Category: Lab Life
The H-index was the brainchild of Jorge Hirsch. It's a method to quantify a researchers impact. (To read more on this, check this entry of mine: What's your h-index.) I was just alerted that Michael Schwartzbach has written a program...
Posted by Alex Palazzo at 4:10 PM • 7 Comments •
Category: Pure Biology
FG repeats found within the nuclear pore complex, form a gel like matrix. It's all nicely explained in a manuscript that recently appeared in Science.
Posted by Alex Palazzo at 9:01 AM • 3 Comments •
December 3, 2006
Category: Misc
... came Stephane Dion to take the leadership of the Liberal Party in Canada. Dion's platform ... (from the CBC) "We cannot afford to miss out on the next industrial revolution: the sustainable economy," Dion said when he announced his...
Posted by Alex Palazzo at 9:02 PM • 8 Comments •
December 1, 2006
Category: Pure Biology
Earlier today I gave our weekly journal club. As usual there is some large scheme/model/godzilla image associated with the intro/summary. Here's mine ... mRNA nuclear export in yeast: Highlighted are 3 major systems. Many proteins are listed, many more are...
Posted by Alex Palazzo at 6:58 PM • 2 Comments • 0 TrackBacks
Category: Map that Campus
What could it be? Come give it your best shot.
Posted by Alex Palazzo at 8:18 AM • 12 Comments • 0 TrackBacks
