biothermodynamics

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Tag archives for biothermodynamics

Our lab has a paper called: “Enthalpic Switch-Points and Temperature Dependencies of DNA binding and Nucleotide Incorporation by Pol I DNA Polymerases” that was just published in BBA (Biochimica et Biophysica Acta): Proteins and Proteomics. The study follows up on an observation and prediction we had made some years ago in a different paper. The study…

Yanling Yang, who just graduated with a Ph.D. from my lab, has a paper in the just published November issue of Biophysical Chemistry. The entire issue of the journal celebrates the 25th Anniversary of a conference called “The Gibbs Conference on Biothermodynamics”, and each of the papers is from the laboratory of one of the…

The laws of thermodynamics are empirical laws – they were not derived from some first principles of the universe: they were derived by doing thousands and thousands of experiments, and then coming up with some relationships that could quantitatively explain all those experiments. In biological thermodynamics, we are at the beginnings of trying to define…

Heat Capacity in Biology 101

Scienceblogs is promoting the writing of “Science 101″ general topic posts all through the “back to school” month of September. So, here is the first in a multi-part series on Heat Capacity in Biology: Heat Capacity in Biology 101: What is it? Heat capacity is basically a proportionality constant. For any substance, the heat capacity…