And now for something completely different... Well, not really, but kind of different. I realize that my niche here has become discussing science-based medicine, evidence-based medicine, and the atrocities committed against both by proponents of so-called "complementary and alternative" medicine, but every so often I need a change of pace. Unfortunately, that change of pace was something I came across in the New York Times on Sunday in the form of a commentary so bad that I seriously wondered if it was a parody or a practical joke. Alas, it wasn't. I'm referring to an article by Andrew Hacker…
It's known as "targeted" therapy, and it's the holy grail of cancer research these days. If you listen to its most vocal proponents, it's the path towards "personalized medicine" that improves survival with much lower toxicity, in which, instead of using the hammer that is chemotherapy, precisely targets specific molecular abnormalities that drive cancer growth. With the advent of the revolution in genomics that has transformed cancer research over the last decade, including the petabytes of sequence and gene expression data that pour out of universities and research institutes, the promise…
Medical therapies should be based upon science. That is a recurrent theme, indeed, the major theme, of this blog. Based on that simple thesis, I've spent the last decade examining "unconventional" treatments and evaluating the scientific basis (or, much more usually, the lack of a scientific basis) for various treatments. Yes, I've looked at other issues, including general skeptical issues, the occasional political rant, Holocaust denial, and, of course the odd self-indulgent bit of twaddle that every blogger engages in every now and then, but I always come back to the question of the…
At least half the time, it seems that when I take on a relatively new topic with every intention of just doing one post about it I somehow end up doing more than one post. I don't know why that is. It just seems to happen. Sometimes, I find something related to but sufficiently different that interests me, sometimes seemingly quite at random. Sometimes someone responds to my post in such a way that I feel obliged to answer. Sometimes, readers make me aware of variations on a theme, so to speak, either in the comments or by e-mailing me links. That's what happened this time. Yesterday I posted…
Many are the forms of quackery to which autistic children are subjected to. It's amazing just how many dubious and dangerous treatments (dubbed "biomedical treatments" or "autism biomed") parents will try in an effort to "recover" their children. Perhaps the most shocking of this quackery that I've recently covered is something called "miracle mineral solution" (MMS), which is in reality nothing more than a powerful bleach. Parents make their autistic children drink diluted MMS, bathe in it, and even take bleach as an enema. They try to claim that what they are using is no more powerful than…
After all the years that I've been writing about vaccines, the science behind vaccines, and how antivaccinationists twist that science to turn what are arguably the greatest medical achievement of medicine and have saved arguably more lives than any other medical intervention devised by human minds into toxic cesspits of horrific chemical corruption that cause autism and destroy children, I thought I had seen it all. And perhaps I have. Sadly, seldum does any new bit of pseudoscience or new fallacious argument trying to claim that vaccines are dangerous surprise me anymore. That didn't used…
A couple of weeks ago, I had a bit of fun with a rather clueless chiropractor by the name of J.C. Smith (JCS), who decided to take a swipe at an organization with which I'm associated, namely the Institute for Science in Medicine (ISM). It was such an inept attack, filled with misinformation, pseudoscience, and logical fallacies, that it was what I like to call a "teachable moment" when it comes to chiropractors and chiropractic. Even more amusingly, JCS promised at the end of his post lambasting ISM as a new "medical mafia" that he would be writing a followup post. I could hardly wait. The…
During this year's TAM, I had the distinct pleasure of accompanying Steve Novella and Michael Shermer to debate an antivaccinationist at FreedomFest, a conservative/libertarian confab that was going on in Las Vegas at the same time as TAM. That antivaccinationist turned out to be Dr. Julian Whitaker, a man who champions Dr. Stanislaw Burzynski and is one of Suzanne Somer's doctors. There's no polite way to put this, Steve Novella wiped the floor with Dr. Whitaker, mercilessly pummeling him with facts, analysis, and logic to the point where even the audience appeared to be grumbling. Even…
Things are getting back to normal here at Casa Orac. it's always a come down after going to TAM and being able to mingle, argue, and party with people who share my skeptical world view. Yesterday was back to reality, though, at least as much as jet lag and sleep deprivation allowed. Fortunately, Monday is a lab day, and I don't have an scheduled patient care responsibilities, and now I'm pretty much back to normal. Even so, I can't do epics like yesterday's post every day even under the best circumstances; so today I'll take a look at a little wafer thin mint to cleanse the palate. I've…
Like so many other skeptics, I just returned from TAM, which, despite all the conflict and drama surrounding it this year, actually turned out to be a highly enjoyable experience for myself and most people I talked to. As I've been doing the last few years, I joined up with Steve Novella and other proponents of science-based medicine to do a workshop about how difficult it is to find decent health information on the Internet, and how the "University of Google" all too frequently puts quackery on the same level as reliable sources of medical information because all that matters for most search…
I was thinking of doing a quickie post about the silliness that's erupted in the antivaccine cranksophere over the IACC hearing that I mentioned yesterday. (Of course, a "quickie" post for me is usually only 1,000 words long, as opposed to the usual 2,000.) Then disaster struck! My hardy, reliable MacBook Air, my main traveling companion for all trips in which I need to do work and/or give a talk died. It died hard (although not like the movies; there were no explosions or fires). It would not boot. Given the craziness at work with grants in the weeks leading up to TAM, I didn't have the talk…
Here we go again... Yes, I'm off to The Amazing Meeting, a.k.a. TAM, where I'll commune with a bunch of fellow skeptics, help do a workshop on science-based medicine, and participate in a panel discussion of so-called "complementary and alternative medicine." Things have been so crazy the last couple of weeks that it turns out that I don't have my talk completely finished, which means I'll be doing what I frequently do for talks, scientific, skeptical, or otherwise: Putting the finishing touches on it during the flight there. Good thing it's a four hour flight. To those of you who are going,…
About a week and a half ago, I took note of a rather unhinged rant by comedian Rob Schneider about vaccines in which he trotted out an antivaccine movement's greatest hits compendium of pseudoscience, misinformation, and logical fallacies, all in the service of opposing California Bill AB 2109. Antivaccine activists hate this piece of legislation in particular, the reason being that it would make it just a little more difficult for parents to obtain philosophical exemptions from school mandates. Right now in California, parents basically just have to sign a form, no questions asked, no other…
Something came up that made me think it would be a good idea to mention a couple of features of the new WordPress template, just in case anyone missed them when I mentioned them before. I apologize to any who might find this repetitive, but there do appear to be some newbies here; so I think it's worth a quick repeat. A commenter who borders on trollish wrote: One thing I forgot. I wanted to congratulate you and the team for closing ‘Evolution and Medicine’ just when you did, leaving the impression that I am EXTREMELY dangerous. Well, I’m not in the least little bit dangerous, but it’s…
One major point I've tried to make over the last few years is that the so-called "individualization" or "personalization" of treatments claimed by practitioners of "complementary and alternative medicine" (CAM) is not "individualization" at all, but rather a sham that appears superficially like individualization but in reality is not. I say that because the "individualization" promoted by CAM practitioners is not based on science and clinical trials. Another point I've been trying to make is that the true "individualization" of treatments will require science, and it will not be easy. In fact…
What would we do without the Internet? It's become so necessary, so pervasive, so utterly all-enveloping that it's hard to imagine a world without it. Given how much it pervades everything these days, it's easy to forget that it wasn't that long ago that the Internet was primarily the domain of universities and large research groups. Indeed, the Internet hasn't really been widely and easily available to the average citizen for very long at all. Go back 20 years, and most people didn't have it. For example, Netscape Navigator, the popular browser that made the Internet accessible, wasn't…
A couple of years ago, I gave a talk to a bunch of Chicago skeptics that was co-sponsored by the Chicago Skeptics and the Women Thinking Free Foundation. At the time, I had no idea that the organization was that new, but I did know that I was very impressed by the turnout to my talk and the camaraderie demonstrated by the two groups, between which there was a lot of cross-pollination. In the interim between then and now, WTF distinguished itself in skeptical activism, but its members are probably best known for its Hug Me I'm Vaccinated campaign. The other day, Elyse announced that Women…
It's rather odd that I'll be writing two posts in a row having to do with a chiropractor, given that chiropractic is at best an occasional topic on this blog. Certainly, I don't hesitate to take on chiropractic when the mood strikes me or, more importantly, when I come across some seriously burning stupid coming from a chiropractor, but other topics tend to dominate my blogging. Let's just put it this way. Two posts in a row on a cancer quack or about antivaccinationists would be nothing the least bit unusual here, but two posts in a row about chiropractors is. As regular readers probably…
Every so often I come across a post by quacks or supporters of quackery that make me wish that we as skeptics and supporters of science-based medicine actually had the abilities and powers attributed to us. I mean, what's the good of being accused of running a conspiracy to crush any sort of "unconventional" or "alternative" medicine if we don't actually have the power to crush unconventional and alternative medicine? Then, sometimes, there are posts that make me really wish that my bloggy skeptic friends and the skeptic organizations to which I belong actually had the power to do the things…
If there's a law that I view as a horrible, horrible, law, it's the Dietary Supplement Health Education Act of 1994 (DSHEA of 1994). It is a law that blog bud and former ScienceBlogs blogger Dr. Peter Lipson has rightly called a travesty of a mockery of a sham, and, quite frankly, I think he has been too easy on it. Clearly, if there is a single instance of a massive triumph of the forces of quackery in the U.S. that I could point to, the DSHEA of 1994 would be it. This particular misbegotten law in essence opened the floodgates for the sale of dubious supplements and turned a relatively…