Here is a photo of one of the Golem computers on which Arieh Warshel and Michael Levitt — this year’s Nobel Prize in Chemistry winners, along with Martin Karplus — did much of their original work.
My dad was a computer programmer at that time, so I have some idea of what their work must have entailed. To this science writer, that makes their feat nothing short of amazing.
The Golem, by the way, which is preserved in the basement of the Weizmann Institute’s mathematics building, was not the first computer at the Institute. The WEIZAC (below) was built at the Institute in the 1950′s, at a cost of one fifth of the Institute’s budget.