When a widely used chemical is identified as an environmental health hazard and targeted for phase-out and elimination, among the most challenging questions for those involved with using and making such a chemical are: What to use instead? and Will the replacement be safe? The US Environmental Protection Agency’s (EPA) report identifying alternatives to the flame retardant hexabromocyclododecane (HBCD) illustrates how difficult those questions can be to answer. It also highlights how important it is to consider the entire life-cycle of finished products when looking for hazardous chemical…