congenital

Image of goldfish from Wikipedia Liver failure or congenital defects can lead to a build-up of ammonia in the brain of mammals resulting in life-threatening swelling, convulsions and comas. For goldfish (Carassius auratus), environmental exposure to ammonia causes reversible swelling of the brain. In a new study published in the American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, researchers wanted to explore how the fish were able to accomplish this. They exposed goldfish to high levels of ammonia for 72 hours which, like mammals, caused oxidative stress …