ICCVAM

ICCVAM authorized two different methods, the bovine corneal opacity and permeability (BCOP) assay and the isolated chicken eye (ICE) assay. These don't use live animals. I'm not exactly sure you could say that this wasn't tested in an animal, but close enough. Or at least that's what the director says. It really don't count as a reduction, but it certainly counts as refinement. As I'm always going on about, this is really a boon for drug and pesticide development and does nothing for risk assessment. Even in the press release (link above), it notes (thankfully): If a positive response is…