Science-y stuff

One of the things I love about the blogosphere is the give and take, the ability of people to comment on each others' work, and the diversity of topics. The conversations that take place in the blogosphere have real value (a value which is so far under-recognized and under-utilized). Without the blogosphere, I would never be exposed to many of the things I read online, such as basic research in neuroanatomy and drug abuse, physiology, and primatology. Interest in primatology is sort of like love of chocolate---I suspect most of us are born with it. As the Bare Naked Ladies sang, "Haven't…
OK, it's time for another science-y post. Usually, I take on something very relevant to my specialty---it's a helluva lot easier to write about stuff I already know. But some basics are just really cool, and worth exploring, even though I'll have to step a bit outside my comfort zone. In this case, it's the heart.  Because I'm venturing a bit on the wild side, I consulted an expert, whose hot, hot science helped illuminate this topic. If you've taken a basic biology course, you probably have some idea of how the human heart works, but understanding can be a bit deeper if we look at the heart…
(NB: as is usual with my more "science-y" posts, oversimplification is the rule. --PalMD) It's been a very long while since I've updated my series on cancer. I keep meaning to, but you know how things go. Lately, though, I've been curious about radiation oncology, the use of ionizing radiation to treat cancers. What set me off was a recent Times article about some pretty crappy practices. Radiation oncology requires a very thorough education in physics and medicine and the field attracts some of the best minds, but no field is immune to unethical behavior (which in this case I feel is…
One of the concepts we often discuss around here is "what is disease?" As we've seen in the discussion of Lyme disease and so-called Morgellons syndrome, this is not always an easy question to answer. Knowing what states are disease states does not always yield a black-or-white answer. The first step is usually to define what a disease is. The next problem is to decide who in fact has that disease. The first question is hard enough, especially in disease states that we don't understand too well. The second question can be equally tricky. To explore the scientific and philosophical…
Science is hard. It often requires us to put aside our beliefs and preconceptions to more accurately understand how the world works. But it is not in any way unimaginative. To paraphrase a wildly brilliant guy, every time a scientist formulates a hypothesis, she must imagine a different world. It can be a very creative process. We advocates for science are often accused of being unimaginative and uncreative. This is false. We are also accused of being closed-minded. This is false. But it is also true. Scientists are very skeptical. To quote one of our regular readers: To state the…
How can a seemingly trivial head injury kill you? To answer this, you need a little anatomy. Your brain is a pretty important organ, and is well protected. It sits inside a thick armor (the skull) and floats cushioned in a bath of cerebral-spinal fluid. It's surrounded by several layers of tissue, and its blood supply is kept relatively separate from the rest of the body (the "blood-brain barrier"). This separation helps keep out toxins and micro-organisms (but is imperfect). Just beneath the skull is a tough, leathery layer called the dura mater. This picture shows the skull cut…
This is just for kicks, and requires a little work. I recently became aware of a dreadful article that I'd love to share with you, but then I thought, "my readers are pretty damned smart; let's see what they have to say first." The article in question, "External Qi of Yan Xin Qigong differentially regulates the Akt and extracellular signal-regulated kinase pathways and is cytotoxic to cancer cells but not to normal cells" just seems ripe for feeding into the dewooificator. Now, the full text is behind a paywall, and it wouldn't do for me to share my full text copy with you. I certainly can…
You've probably read about the current Salmonella outbreak. It's a fine example of what can happen when food is produced and distributed on an industrial scale---even one small contamination event can spread widely in the food supply, and there isn't much of a system in place to follow the trail of contaminants. Others have covered the public health implications of this outbreak, so I'd like to examine some other facts that make this outbreak disturbing. Salmonella likes non-human animals Some species of Salmonella cause typhoid fever. Typhoid fever, a nasty epidemic disease of humans, is…