In his post last Friday, Peter did a very nice job of introducing the the counter-intuitive idea that having too little fat, rather than too much, causes many of the metabolic problems of obesity. Today I thought it would be good to continue on with this theme and to focus on some of the mechanisms that explain this strange relationship. Let's begin where Peter ended off:
Currently, the emerging theory of why obesity is associated with metabolic disease risk suggests that it is not the excess amount of fat that results in problems - but rather, it is the inability of the fat tissue (…
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