transcription factors
sporte | March 30, 2009
Watching the chIPs roll in,
then I watch them roll away again,
I'm just sitting on the DNA,
wasting time
(sung to the tune of "Sitting on the dock of the bay" by Otis Redding)
Hesselberth et.al. recently published a paper about digital genomic
footprinting that blew me away because it has so much potential. The authors used DNAse I and Next Generation DNA Sequencing to map every site in the yeast genome where a protein might be sitting.
Since I used to do similar kinds of experiments, albeit on a much, much smaller scale, this sort of publication boggles my mind. It's only recently that I've…