Gene Expression

Important papers on recent human evolution

This post is more of a personal note…here are three papers that are really cool must reads:

Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante CD, et al. (2007) Localizing Recent Adaptive Evolution in the Human Genome. PLoS Genet 3(6): e90 doi:10.1371/journal.pgen.0030090

Voight BF, Kudaravalli S, Wen X, Pritchard JK (2006) A Map of Recent Positive Selection in the Human Genome. PLoS Biol 4(3): e72 doi:10.1371/journal.pbio.0040072

Tang K, Thornton KR, Stoneking M (2007) A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome. PLoS Biol 5(7): e171 doi:10.1371/journal.pbio.0050171

E.T. Wang, G. Kodama, P. Baldi, R.K. Moyzis, Global landscape of recent inferred Darwinian selection for Homo sapiens, Proc. Natl. Acad. Sci. USA 103, 135-140 (2006). doi:10.1073/pnas.0509691102

All 4 papers are Open Access! The statistical & computational techniques can be hard to follow sometimes, but these HapMap datasets are the tip of the iceberg, so get comfy and start learning if you want to be able to follow the blow-by-blow over the next few years….

P.S.: If you dig flies, read Evolgen.


  1. #2 razib
    September 29, 2007

    thanks! i kept looking for that in PLOS Biology 😉 why the hell did they put in in genetics?

  2. #3 Sandgroper
    September 30, 2007

    Mate, if you’re from Oz, the last thing you need is more bloody flies.

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