Important papers on recent human evolution

This post is more of a personal note...here are three papers that are really cool must reads:

Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante CD, et al. (2007) Localizing Recent Adaptive Evolution in the Human Genome. PLoS Genet 3(6): e90 doi:10.1371/journal.pgen.0030090

Voight BF, Kudaravalli S, Wen X, Pritchard JK (2006) A Map of Recent Positive Selection in the Human Genome. PLoS Biol 4(3): e72 doi:10.1371/journal.pbio.0040072

Tang K, Thornton KR, Stoneking M (2007) A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome. PLoS Biol 5(7): e171 doi:10.1371/journal.pbio.0050171

E.T. Wang, G. Kodama, P. Baldi, R.K. Moyzis, Global landscape of recent inferred Darwinian selection for Homo sapiens, Proc. Natl. Acad. Sci. USA 103, 135-140 (2006). doi:10.1073/pnas.0509691102

All 4 papers are Open Access! The statistical & computational techniques can be hard to follow sometimes, but these HapMap datasets are the tip of the iceberg, so get comfy and start learning if you want to be able to follow the blow-by-blow over the next few years....

P.S.: If you dig flies, read Evolgen.

Tags

More like this

Proto Stephen Jay Gould OMFSM you are not going to believe this. Over at the University of Chicago, someone is making a terrible fool of themselves. It is hard to say if this is Shankar Vedantam, the Washing Post Staff Writer, or Patterson Clark of the Washington Post or someone else. The…
In a post at the Panda's Thumb, Ian Musgrave cites this paper by Bakewell et al claiming that 154 genes out of 13,888 surveyed show evidence for adaptive evolution in humans since the divergence with chimps (this is the "chimps more evolved than humans" paper). Ian brings this up in a discussion of…
Not all regions of the genome are equal in the eyes of evolution. For example, natural selection is more effective on genes in regions of higher recombination. We have known this for a while. The connection between recombination rate and natural selection was nicely refined when it was shown that…
Last year, Katie Pollard and colleagues published a couple of papers in which they identified regions of the human genome that had recently undergone an acceleration in their rate of evolution and characterized the expression pattern of an RNA gene located in one of those regions. The RNA gene is…

Mate, if you're from Oz, the last thing you need is more bloody flies.

By Sandgroper (not verified) on 30 Sep 2007 #permalink