A few weeks ago I posted on how population bottlenecks can convert dominance variance into additive genetic variance. This is important because it is additive genetic variance that is relevant for population level directional selection upon quantitative characters. Now agnostic posts on how epistatic variance can be converted into to additive genetic variance.
- Log in to post comments
More like this
I have stated before that additive genetic variance is the relevant component of variance when modeling the response to selection in relation to a quantitative trait. In other words:
Response = (additive genetic variance)/(total phenotypic variance) X Selection
Consider height, which is about 80%…
I know I've posted on this topic before, but I thought I'd revisit it again. You do know that sometimes population bottlenecks can actually result in more variation being freed up for selection? This may strike you as a bit strange; after all, the power of selection to effect phenotypic change is…
Jim Manzi has a long post up on epistasis, that is, gene-gene interactions:
We could call this process of competing algorithms struggling to find the best solution as fast as possible "meta-evolution". That is, each potential search method must compete for survival. The fact that the algorithm that…
A worthy (so I believe) repost from my other blog....
[begin repost]
Several years back David wrote about Sewall Wright's Shifting Balance Theory. If you know much about the history of mathematical genetics you know that R.A. Fisher and Wright's disputes over the importance of population…