As part of my ongoing effort to make sure that I never run out of blogging material, I subscribe to a number of quack e-mail newsletters. In fact, sometimes I think I've probably overdone it. Every day, I get several notices and pleas from various wretched hives of scum and quackery, such as NaturalNews.com, Mercola.com, and various antivaccine websites. I think of it as my way of keeping my finger on the pulse of the antiscience and pseudoscience wing of medicine, but I must admit that I don't really read them all, but they do allow me to know what the quacks are selling and what new…

The Human Genome Project (HGP) was one of the most massive scientific undertakings in recent years and, from a basic science and technology development standpoint, one of the most productive. The data gained formed the basis of the genomic revolution. And "revolution" is the right word. A mere 12 years after the human genome sequence was first published in papers in Nature and Science, we now have petabytes of sequence data pouring out of universities, research institutes, and genomics institutes. Sequencing a genome, which took several years to do for the HGP and cost billions of dollars,…

In common colloquial usage, there is a term known as "gaydar." Basically, it's the ability some people claim to have that allows them to identify people who are gay. Whether gaydar actually exists or not, I don't know, but I claim to have an ability that's similar. That ability is the ability to sniff out antivaccinationists. Over the last decade, I've become very good at it, so much so that it's almost instinctual and rarely wrong. My guess is that it's nothing more than my having internalized all the tactics and tropes that antivaccinationists like to use to the point where I don't need to…

I sense a disturbance in the skeptical blogosphere. It is something that I half-expected, but, even so, it nonetheless somewhat surprised me when it arrived in the form of comments on my blog and e-mails from readers, fellow supporters of science-based medicine, and others asking me what I thought. In a way, it makes me glad that I didn't blog about this back on Monday, when the study that is the focus of this disturbance was published. Had I written about it then, all I would have had as fodder was the study itself. However, waiting a couple of days has allowed me to see the reaction of the…

One of the overarching issues, if not the overarching issue that makes so-called "complementary and alternative medicine" (CAM)—or, as it's now more commonly called, "integrative medicine"—so problematic is prior plausibility. It's also one of the most difficult to explain to the lay public, because to someone not trained in science it can sound like not being open-minded. I like to joke about this whole concept by saying that it's good to be open-minded but not so open-minded that your brains fall out. In other words, the main difference between science-based medicine (SBM) and evidence-…

Although I focus mostly on medical topics, such as vaccines, alternative medicine, and cancer quackery, I don't limit myself to such topics. True, I used to write a lot more about evolution and creationism, the paranormal, and other standard skeptical topics, but over the last couple of years I've realized where my strength is and where my niche is. So I continue to do what I do, but that doesn't mean I've lost interest in those topics. I've just learned that there are those who can do them as well as I can, while the number of people who can do what I do with respect to quackery and medical…

On the antivaccine front, this year began with antivaccine hero Andrew Wakefield filing suit against investigative reporter Brian Deer, the BMJ, and Fiona Godlee (the editor of BMJ) for libel based on a series that Deer published in the BMJ outlining the evidence for Wakefield's scientific fraud in his (in)famous 1998 Lancet case series. This resulted in a massive rallying of the antivaccine troops around Wakefield, as well as temporarily making him appear relevant again after so many much-deserved humiliations and defeats, in the wake of his having had his license to practice medicine in the…

Believe it or not, after nearly eight years blogging and around five years before that cutting my skeptical teeth on that vast and wild (and now mostly deserted and fallow) wilderness that was Usenet, I have occasionally wondered whether what I'm doing is worthwhile. Sometime around 1998, after I first discovered Holocaust denial on Usenet, and a year or so after that, I found the home of all quackery on Usenet, misc.health.alternative. From around 1998 to 2004, Usenet was my home, and that's where I fought what I thought to be the good fight against irrationality, antiscience, and quackery.…

I must admit, there are times when I see something that someone else has written and, in a fit of intense envy, wish very much that I had written it. This is just such a time, and Tony Ballantyne has written just such a piece. Even better, his piece, entitled If only..., was published in Nature! That's right, the editors of Nature itself agree (or at least thought it interesting enough to publish): No science for you! What are you waiting for? Read it! Of course, it's all a fantasy. In particular, I like the part asking why so many people are proud to be "bad at math" who would be utterly…

Long, long ago, seemingly in a galaxy far, far away, I first encountered quackery on the Internet. Because I am a cancer surgeon, naturally I gravitated towards cancer quackery at first. Believe it or not, it was quite some time after that before I started to take an interest in what has become a major focus of this blog, the antivaccine movement and the misinformation it spreads. Both are equally damaging in their own way. True, these were back in the deep, dark days when I used to cruise various Usenet newsgroups, ranging from alt.revisionism (Holocaust denial), sci.skeptic (of course!),…

About a month ago, I deconstructed a typically dishonest and deceitful attempt by that Overlord of Quackery on the Internet (in my opinion, of course), Joe Mercola, to claim that the acellular pertussis vaccine doesn't work. It was a typical Mercola bit of prestidigitation that, as so much antivaccine propaganda does, took a grain of truth (that there have been outbreaks among vaccinated populations) and ran with it to construct a fantasy world in which pertussis outbreaks are somehow an indictment of all vaccines, which, of course, don't work at all, ever, under any circumstances, anywhere…

Over the long weekend, I came across a bunch of things that in normal times I would have blogged about, but because I was trying to chill, work a little on the yard, and also work a bit on grants, I intentionally took Monday off of blogging. As I get back into the swing of things, work-wise, blogging-wise, and otherwise, I thought it would be a good thing to make sure not to miss at least one thing I saw that doesn't require a fill Orac-length discussion but should be pointed out nonetheless. It's a little blurb that appeared on the antivaccine website complaining about vaccination…

Why is it after a three day weekend, it always feels as though I have to "catch up"? After all, it's only one day more than the average weekend, and I didn't really do anything that different. A little yard work, out to dinner, a bit of grant writing, a bit of chilling, that's it. Maybe it's because pseudoscience and quackery never rest, while, my never-sleeping, computer-inspired moniker notwithstanding, I do. I have to, particularly as age creeps up on me. In any case, right before the Labor Day weekend, I felt a disturbance in the antivaccine crankosphere. It began Wednesday, with a post…

For my international readers, it's a holiday here in the U.S. That means I plan on taking it easy, which means I've decided on doing, in essence, a "rerun." I chose this particular rerun based on my post from last Thursday. I thought that rerunning this particular post is a good reminder of what the cost of eschewing science-based therapy for breast cancer can be, and that price is horrible. This particular post dates back to 2006; so, if you haven't been reading the awesomeness that is my blog that long, it's new to you. I'll be back with new Insolence tomorrow. I've written before about how…

Here we go again. Every so often, criticism of the antivaccine movement builds to the point where it extends beyond the blogosphere to enter the national zeitgeist in a way in which people other than blogging geeks like myself start to take notice. It happened a few years ago, when washed up actress Jenny McCarthy teamed up with the antivaccine propaganda group Generation Rescue to sell her story of how she believes that vaccines caused her son Evan's autism and managed to score an appearance on The Oprah Winfrey Show. It happened again three years ago, as preparations for the H1N1 pandemic…

As a cancer surgeon specializing in breast cancer, I have a particular contempt for cancer quacks. In particular, that contempt smolders and occasionally bursts in to flames right here on this very blog and, to a lesser degree, elsewhere, when I see instances of such quackery applied to women with breast cancer. They are, after all, the type of patients I spend all my clinical time taking care of and to whose disease my research has been directed for the last 13 years or so. That's why I keep revisiting the topic time and time again. Unfortunately, over the years, when it comes to this topic…

If there's one thing that practitioners of pseudoscientific medicine crave more than anything else, it's respectability. Believing that science-based medicine is corrupt and that their woo is as good or better, they delude themselves into thinking that they can function as well or better than primary care doctors practice and therefore should be given the same privileges that physicians are granted. To them, it makes sense. On any objective basis, however, it does not. The reason is simple. The two most common "disciplines" that seek the same scope of practice as primary care doctors are…

I might as well lay it on the line right at the beginning. It's not as though it will surprise my regular readers given what I've been writing here, most recently about when Rob Schneider played the Nazi card to express his opposition to California Bill AB2109. It's a bill that does something very simple and very necessary; basically it requires that parents seeking a nonmedical exemption from school vaccine mandates actually visit a health care professional to provide informed consent before an exemption is granted. Yet, even suggesting that maybe—just maybe—nonmedical exemptions are too…

If there's one thing I've been railing about for the last few years, it's how scientific and medical studies are reported in the lay press. It seems that hardly a week passes without my having to apply a little Insolence, be it Respectful or not-so-Respectful, to some story or another, usually as a result of the story having caught my interest, leading me to look up the actual study in the peer-reviewed literature. This is something I've learned the hard way that I have to do, having been burned a couple of times in my early blogging career. Sometimes, even now, I forget. For example,…

When I first started this blog, I had little idea of what I was in for. I thought I had some idea from having read a bunch of blogs and found role models whose blogging style I tried to emulate back in those early days, long before I developed the persona and writing style that most of my readers love and quacks and antivaccinationists really hate. Now that I've been at it for nearly eight years, there's very little that surprises me. Much of the quackery, pseudoscience, and nonsense that I see is stuff that I've seen before and possibly blogged about multiple times before. I'm starting to…