Nobel in Medicine goes to…

I've known for years that this was going to happen: Mario Capecchi, Oliver Smithies and Briton Martin Evans have won the Nobel Prize in Medicine for their work on targeted gene mutations. If you're interested in what kinds of work they've done, I described one paper on Hox regulatory evolution, and this work on the evolution of the Hox code wouldn't have been possible without their knockout techniques.

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No IgNobels here, the 2007 Nobel Prize for Physiology or Medicine has been awarded to Mario R. Capecchi, Martin J. Evans, and Oliver Smithies for a technique that is so incredibly important to modern biomedical research that it's a wonder they didn't get the prize before: This year's Nobel…
This morning, Drs Mario R. Capecchi, Martin J. Evans, and Oliver Smithies were jointly awarded the Nobel Prize in Physiology or Medicine for their discoveries of "principles for introducing specific gene modifications in mice by the use of embryonic stem cells." The technology for homologous…
I somehow managed to lose track of time for a bit, and forgot that it was Nobel season until I saw this morning's announcement that the 2007 Nobel Prize in Medicine hase just been announced, going to Mario R. Capecchi, Sir Martin J. Evans, and Oliver Smithies, for their discoveries of principles…
Dr. Oliver Smithies, the Excellence Professor of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, NC, USA, together with Mario R. Capecchi and Martin J. Evans, won this year's Nobel Prize in Physiology and Medicine: This year's Nobel Laureates have made a series of…

PZ, this has to be either a mistake or a huge, sick joke!

According to brain surgeon, Dr. Mikey Egnor (read that Brain Surgeon, like a rocket scientist only with brains) evolution has NO application to medicine.

How could brain surgeon Dr. Egnor <--- Brain Surgeon, be wrong?

Obviously, the Nobel Prize committee has been fooled.

No, wait, wait! Not fooled. No, bought off by the Darwinian Pressure Group, Delta Pi Gamma. Yeah, that makes total sense.

Congratulations to Mario. It's nice to see the University of Utah has one smart professor.

By Christian Burnham (not verified) on 08 Oct 2007 #permalink

Took them long enough.
Congrats Mario. Developmental biology loves you.

Well-deserved. Transgenic technologies have really sped up research on development and disease. Bravo, I say.

... Doc. I don't think "How could brain surgeon Dr. Egnor" is a complete sentence. And, more saliently: a brain surgeon is not a scientist by default. I also failed to locate an actual entity either called the "Darwinian Pressure Group", nor is could I find a "Delta Pi Gamma".

I'd say my tone in my comments here are generally pretty mild, but, for you, I'd say you're a blithering idiot.

If this was meant to be a posted joke, then I apologize, and congratulate Doc Bill in emulating the general style of total cerebral meltdown often exhibited by anti-science-sheep.

Oops. Typo. Nix the "is" in "nor is could I".

Actually, Inky, that was an incomplete question!

I used an angle bracket to make an text-graphic arrow and the blog thought it was an incomplete HTML tag and ate it.

You can go to the Panda's Thumb and read all about the Darwinian Pressure Group, Delta Pi Gamma, that was founded following an accusation by the Discovery Institute that various institutions and school boards had been forced to oppose "intelligent design" due to "darwinian pressure groups." We thought we'd help the DI with truth and accuracy in reporting by creating such a group.

For example, we're putting pressure on Baylor right now by threatening to block funding of Bill's Sports Arena and Tire Center, and I think we're having the desired effect.

As for Egnor, who believes in the duality of mind and brain, you will have to research him yourself. Fair warning, though, the stupid will burn your brain. Hey, maybe that's how he gets patients.

Finally, as for being a "blithering idiot" my wife tells me that all the time. I look upon it as my greatest strength.

p.s. If you want to join Delta Pi Gamma, I'll let you know where to send the dues.

I have a soft spot for the discovery of telomerase and I was hoping it would get the prize this year. Elizabeth Blackburn och Carol Greider would raise the number of women among the laureates which would be great in so many ways. But the telomerase in itself I think merits the prize regardless.

That's not to say that this year's prize winners are any less worthy of course. I'm really, really looking forward to the lectures here in Uppsala. Last year I had the fortune of meeting both Drs Mello and Fire and I hope to repeat that this year!

By the way, here in Sweden all the animal rights activists are really making a fuss over this year's prize. It's going to be interesting to see how it plays out in the media.

och?

Oh.. Swedish. That's pretty cool, actually. I think I'll start using it..=)

The award goes "for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells".

Mmmm, ¿embrionic stem cells?, ¿any message for the religous right?

By Rolando Aguilera (not verified) on 08 Oct 2007 #permalink

Okay, Doc. I guess my sense of humor program was malfunctioning today.

Re: membership dues, er, no, that's okay. Maybe with my next monthly stipend allocation.

Daniel:

I have a soft spot for the discovery of telomerase and I was hoping it would get the prize this year. Elizabeth Blackburn och Carol Greider would raise the number of women among the laureates which would be great in so many ways. But the telomerase in itself I think merits the prize regardless.

Blackburn was my department's pick, too. Except for maybe another one of our own. :-)

Funnily enough, the prize is called the Nobel Prize in Physiology or Medicine. So, Cappecchi, Smithies and Evans have won the Nobel Prize in physiology or medicine.

By David Marjanović, OM (not verified) on 08 Oct 2007 #permalink

Evviva Mario, and congratulations from an expat Italian!
How come Italians have always to migrate elsewhere to accomplish great things? (I'm thinking of Fermi, Modigliani, etc.)...
Perhaps it's true that prophets are never welcome...
Nahhh.

Ciao and bravo!

~K

Mario Capecchi, like Peter Irons and Stephen J Gould, is a graduate of Antioch College. That little school in Ohio that is planing to close next summer, unless the alumni can save it.

By molluskman (not verified) on 09 Oct 2007 #permalink

Funnily enough, the prize is called the Nobel Prize in Physiology or Medicine. So, Cappecchi, Smithies and Evans have won the Nobel Prize in physiology or medicine.

By David Marjanović, OM (not verified) on 08 Oct 2007 #permalink