alzheimer's disease

A week ago, I wrote about an example of one of the most common topics on this blog, the infiltration of pseudoscientific medicine and outright fantasy into academic medicine, a trend I like to refer to as quackademic medicine. The institution was George Washington University, and the dubious intervention was something called the MEND™ Protocol, which is sold as a treatment for Alzheimer’s disease by Muses Labs. As I described, it’s a protocol that appears to rely on a proprietary computer algorithm of some kind that, according to Muses Labs, produces a “personalized” treatment plan for…
A recurring theme of this blog is to shine a light on what I like to call “quackademic medicine.” I didn’t invent the term, but I’ve made it mine. Basically, quackademic medicine is a term that very aptly describes what’s going on in far too many academic medical centers these days, which is the infiltration of pseudoscientific medicine and outright quackery in the form of “complementary and alternative medicine” (CAM). Of course, the more recent term for CAM is now “integrative medicine,” which was coined to imply the “integration” of alternative medicine with science-based medicine as…
If there’s one characteristic of supporters of dubious medicine, it’s that they detest criticism. Whereas your average skeptic might not like criticism—sensitivity to criticism being a human trait and all—science- and evidence-based criticism tends to drive dubious medical practitioners (and, I might add, promoters of various other forms of woo) into paroxysms of anger. Not infrequently, because they can’t refute such criticisms with science and evidence, they respond by lashing out, by going on the attack. That lashing out can take many forms, from simply writing abusive posts about their…
With the aging of the population, one of the most feared potential manners by which more and more of us will leave this earth is through Alzheimer's disease or other forms of dementia. And it is a scary thing, too. Having valued my intelligence all my life and in particular enjoying the intellectual stimulation that I derive from my job, not to mention from blogging and contemplating science outside my realm of expertise, like many people I fear Alzheimer's disease at least as much as cancer or heart disease, possibly more. Imagining the slow decline in my faculties to the point where I can…
Student guest post by Ron Bedford The NYT (Kolata, 2010) recently published a story we'd all like to believe in. After their "lab's usual end-of-the-week beer hour," two Harvard neurology researchers noticed similarities between not only genes associated with both the innate immune system and Alzheimer's disease (AD), but structures, characteristics, and actions of selected proteins as well. Dr. Rudolph E. Tanzi, Dr. Robert D. Moir, and their team found "striking similarities" between the well-known innate immune system protein, LL-37, and amyloid β-protein (Aβ), long considered a waste…
ALZHEIMER'S Disease is the most common form of dementia, affecting an estimated 30 million people worldwide. The cause of the condition is unknown, but the prime suspect is amyloid-beta (Aβ), a 42-amino acid peptide which accumulates within neurons to form insoluble structures called senile plaques that are thought to be toxic. Aβ is synthesized in all neurons; it is associated with the cell membrane, and is thought to be involved in cell-to-cell signalling, but its exact role has eluded researchers. A new study published in the open access journal PLoS One now shows that Aβ is a potent…
The always-outstanding neuroblogger, SciCurious, put up an excellent post overnight on a presentation she saw at the current Annual Meeting of the Society for Neuroscience (SfN) in Chicago. Therein, she wrote about a poster presentation she saw on the relationship between iron, cholesterol, and Alzheimer's disease. All was quite well until near the end of her post. That is where my writer's block of the last week dissipated and manifest itself as a blogpost-length comment. This is a lovely post otherwise but you've obviously been drinking if you think you could get away with "an enzyme…
tags: Alzheimer's Disease, Terry Pratchett, research, fund raising, medical research Thanks to one of my readers, I just learned that atheist and writer Terry Pratchett, author of the bestselling Discworld novels, has been diagnosed with a rare form of Alzheimer's disease. He has donated half a million pounds (approx $1 million) to Alzheimer's research and appeared in the media highlighting the low levels of research funding that Alzheimer's disease receives. As a result, millions of loyal readers from around the world have responded and are helping to match Terry's donation. If you would…