cancer

New research at the Institute may offer a sliver of hope for treating “triple-negative” breast cancer. “Triple-negative” refers to the fact that the breast cancer cells are missing the three different receptors targeted by the currently available drugs, for instance Herceptin and steroid hormone blockers. This type of cancer also tends to be fairly aggressive, and the risk of early recurrence is higher than for other types of breast cancer. Triple-negative breast cancer cells do have other receptors – particularly EGFR, a growth factor receptor that would seem to be a good target for…
Image of camel from ukmedix news. Researchers from King Abdulaziz University (Jeddah) have tested the effectiveness of micro and nanoshells for delivering a substance from camel urine, PMF701, thought to be a cure for cancer. These findings will be presented at the 2nd Biotechnology World Congress (Feb 18-21). PMF701, not yet approved by the Saudi Food and Drug Authority, is currently in clinical trials. In a quote published by SciDev.net, the head of the university's tissue culture unit and the principal investigator of the project Faten Abdel-Rahman Khorshid stated, "We made a natural…
This is one of the cool ideas not included in the 1800 human gene therapy trials because its still in animal models, not humans: Preclinical Therapy of Disseminated HER-2+ Ovarian and Breast Carcinomas with a HER-2-Retargeted Oncolytic Herpesvirus If Ive said it once, Ive said it 1000 times: 'Cancer' is not a monolithic entity. We have not 'cured cancer' because there are lots and lots and lots of different kinds of cancers. Some ovarian cancers and some breast cancers have a protein upregulated, HER-2. Scientists have capitalized on this observation to create anti-tumor drugs that focus on…
It's good to see that the organizers of the Ottawa Regional Cancer Foundation finally realized its mistake: Actress Jenny McCarthy has been dumped again. McCarthy won't be in Ottawa for Bust A Move. The Ottawa Regional Cancer Foundation reacted today to a public backlash in signing the anti-vaccine campaigner to the Ottawa breast health fundraiser. As I said before when I first noted the extreme idiocy of their decision to feature an anti-science twit like Jenny McCarthy, whose antivaccine activism directly endangers cancer patients, I can't figure out what the organizers were thinking. I…
I'm sure this is a case where someone thought it was a good idea at the time. Unfortunately, it's not. It's an astoundingly bad idea: The Ottawa Regional Cancer Foundation is bringing McCarthy to town March 2 to headline its annual Bust a Move fundraiser as a guest fitness instructor. But the actress, author and former Playboy playmate is perhaps best known these days for her unconventional views on autism, specifically her anti-vaccination writings. Her son Evan Joseph was diagnosed with autism in 2005, but McCarthy says now her son is in “recovery” and is doing much better. McCarthy has…
  You may recall a prior blog entry about a new experimental treatment for bone cancer in dogs. Researchers are increasingly studying canine cancer and discovering that it is caused by some of the same genetic mutations that cause cancer in humans.   Shown in the image above is Jasper, a 7-year old dog that has lymphoma, cancer of the immune system (white blood cells) that is similar to non-Hodgkin lymphoma that afflicts people. Researchers are hoping that studying the DNA of dogs with cancer may lead to treatments for not only dogs, but also people.  The first national canine tumor bank,…
Could we have taken action earlier to prevent harm from tobacco, asbestos, and lead?  That's the question at the core of the European Environment Agency's (EEA) collection of case studies, which was released this month as Volume 2 "Late lessons from early warnings: science, precaution, innovation." The publication features articles on those nefarious health hazards, as well as ones about beryllium, Bisphenol A, the pesticides DBCP and DDT, mercury, perchlorethylene, and vinyl chloride.  Protecting ecosystem, including aquatic environments exposed to ethinyl oestradiol (synthetic estrogen used…
Hey remember how I told you all scientists are using herpes, the regular-ol much hated cold-sore virus, to treat/cure cancers? The approach has left us with miraculous effects... or no effects at all. I mean, half of the melanoma patients lived A LOT LONGER than they were supposed to, several of them ending up with no evidence of disease... But that also means that half werent helped at all. HSV-1 couldnt help a child with rhabdomyosarcoma... when it was 'supposed' to work so well. What happened? Of course that question has a collection of complex answers, and there are lots of scientists…
The weekend was busy, and I was working on grants, which meant that I could only come up with one post of Orac-style length and depth. Sadly, it wasn't for this blog. Fortunately, C0nc0rdance came to the rescue with a must-watch video about our old friend Stanislaw Burzynski. He's the guy who claims to treat cancer more successfully than conventional medicine—and not by a little—using chemicals he calles "antineoplastons," which he originally isolated from urine but now synthesizes in a laboratory. More recently, he's been claiming to deliver "personalized gene-targeted cancer therapy" that…
While I'm using my blog as an announcement platform today, I would be remiss not to mention that tomorrow is Dr. Stanislaw Burzynski's birthday, and the Skeptics for the Protection of Cancer Patients are still raising money for St. Jude's Children's Hospital in order to try to get Dr. Burzynski to do something good for cancer patients for a change. The beauty of it is that, even if Burzynski declines, as is likely, there'll still be a nice big donation to a real cancer center that does real good for children with cancer, which is in marked contrast to Burzynski. Harriet Hall has joined in the…
As I contemplated how I wanted to start the blogging week, I thought that I should probably again plug Bob Blaskiewicz's campaign to provide Dr. Stanislaw Burzynski, the Houston doctor who for the last 35 years has been treating patients diagnosed with advanced stage and terminal cancers with something he calls antineoplastons (ANPs), with a most excellent "gift" for his 70th birthday. This he does despite the astounding lack of compelling evidence that ANPs are actually effective against cancer, none of which stops him from charging patients exorbitant amounts of money, sometimes upwards of…
by Kim Krisberg Dr. Paul Demers says he frequently finds himself having to make the case for why studying workplace exposures to carcinogens is important. Oftentimes, he says, people believe such occupational dangers are a thing of the past. "A lot of people are still developing cancer and dying from cancer due to workplace exposures, but only a small fraction of those are compensated, so people may think the magnitude of this problem is small," said Demers, director of the Occupational Cancer Research Centre in Ontario, Canada. "I wanted to have better data." And in just a few years, he will…
Eric Merola doesn't much like me. Actually, no one who is an apologist for Dr. Stanislaw Burzynski, a.k.a. "Stan the Man," who over 30 years ago unleashed antineoplastons on unsuspecting cancer patients, much likes me. It's not surprising. As you might recall, antineoplastons are chemicals that Burzynski found in the urine of cancer patients and that (or so he claims). Claiming that antineoplastons were endogenous inhibitors of tumor growth made by the body and of which cancer patients are deficient, thus allowing cancer to grow, he embarked on a campaign to treat cancer patients with them.…
Everything Everything gives you cancer Everything Everything gives you cancer There’s no cure, there’s no answer Everything gives you cancer - Joe Jackson I don't write about nutrition as much as other topics because I'm not as knowledgeable about it as I am about, say, cancer, vaccines, and what constitutes good medical evidence. (I am, however, trying to become more knowledgeable.) Even so, I was thinking. After my post a week ago in which über-quack Joe Mercola unexpectedly gave a glowing introduction to a paean of praise for bacon and my post yesterday in which a credulous fellow by the…
With five days left in calendar year 2012, the Obama Administration released to the public its current plan for regulatory and deregulatory activities, including those affecting individuals exposed to hazards in their work environment.  Executive Order 12866 (adopted in 1993) says the annual regulatory plan “shall be” published in October, and the Regulatory Flexibility Act (5 USC 602) says the semi-annual regulatory agendas “shall” be published in April (Spring) and October (Fall).   The Obama Administration failed to meet either of these deadlines, and simply issued for 2012 one regulatory…
Today's post will be relatively brief (for an Orac post, that is). The reason is that it's some very sad news that depresses me greatly. It's also because I don't want to distract too much from the announcement I'd like to highlight. About a month and a half ago, around the same time that Stanislaw Burzynski managed to get off on a technicality, with the Texas Medical Board agreeing to dismiss its case against Burzynski because it apparently couldn't go after him for treatment decisions made by doctors he hired, I met an unfortunate girl named Amelia Saunders. Amelia had been diagnosed with a…
It is an indisputable axiom that everything tastes better with bacon. Well, almost everything. As much as I love bacon, whenever I watch one of those cooking competition shows on the Food Network, like Iron Chef America, in which the secret ingredient is bacon, I can't figure out how putting bacon in ice cream works. OK, so maybe it's almost an axiom. There are a few exceptions. But the fact remains that the vast majority of foods do taste better with some bacon. Of course, the problem with bacon is that it's widely accepted that it's not particularly good for you. Because it is a processed…
If there's one claim that practitioners of "holistic" medicine frequently make, it's that "complementary and alternative medicine" (CAM) or "integrative medicine" or whatever the term du jour for the combining of quackery with science-based medicine is these days is allegedly so much better than "conventional" or "allopathic" medicine (or whatever disparaging term "holistic practitioners" prefer) at preventing disease and keeping people healthy. The claim is a load of fetid nonsense, of course, but it sounds convincing on the surface. After all, CAM practitioners have been disturbingly…
Note: Orac is away somewhere warm recharging his Tarial cells for further science and skepticism. In the meantime, he is rerunning some of his favorite posts. Given that the blog seems to have been infiltrated with Burzynski trolls again and Eric Merola threatens to make a sequel to the execrable movie he made about Burzynski a couple of years ago, now seems a perfect time to rerun a post of Orac's from about a year ago. In fact, now might be a perfect time to rerun these posts. Indeed, maybe I'll even rerun the whole trio, as Orac has been thinking he needs to do a major update and…
A recently published case-control study involving more than 2,100 women in southern Ontario, Canada reported a strong association between being employed in the automotive plastics industry and breast cancer. The researchers recruited the 'case' subjects between 2002-2008 among newly diagnosed breast cancer patients and the randomly-selected controls from the same geographic area.  The researchers examined a variety of risk factors for breast cancer (e.g., reproductive history, age) and collected data on the women's employment history.  Elevated odds of breast cancer were found among women…