cancer
oracknows | December 3, 2009I'm beginning to understand why evolutionary biologists are so sensitive about how creationists abuse and twist any research that they think can be used to cast doubt upon evolution. Whenever there is research that changes the way we look at evolution or suggest aspects of it that we didn't appreciate before, where scientists get excited because they see an opportunity for better understanding of evolution, creationists see a chance to use it to launch specious and fallacious attacks against evolution. Sadly, there is no shortage of creationists willing to make fools of themselves to try to…
oracknows | November 21, 2009Before I try to leave this topic for a while (which, like so may topics in the past, has temporarily taken over the blog for the last few days), one of the comments I've kept hearing since I started blogging about the new USPSTF mammography guidelines is something along the lines of, "Well, if the government runs health care, naturally politics will impact any attempts at science-based guidelines. That may be true, but in fact excessive politicization has always been a problem in that area, particularly for breast cancer. There's a good interview with to Dr. Barron Lerner, associate professor…
terrasig | November 20, 2009
In September we posted "M.D. Anderson name misused in Evolv nutraceutical water advertising," detailing the not-exactly-truthful claim by a multilevel marketing company that their bottled water product was "tested" by one of North America's premier teaching and research hospitals.
A flurry of search engine hits to this post raised my attention to the fact that the The University of Texas M.D. Anderson Cancer Center has now initiated legal action against the makers of Evolv. Cameron Langford at Courthouse News Service reports:
Two companies are pushing bottled tap water with false claims…
oracknows | November 20, 2009As I discussed in detail when I analyzed them, the new USPSTF recommendations for screening mammography for breast cancer have sparked a debate that has degenerated from a scientific and public policy debate into pure emotional rhetoric. When last I visited this topic, yesterday, I had intended it to be my last post for a while, perhaps ever. However, the amount of idiocy that I was dealing with became so overwhelming and the post grew to even huger than Orac-ian proportions. So I decided to split the post into two parts, because the particular argument I'm about to discuss deserves its very…
oracknows | November 19, 2009I knew when I first heard about them that the new United States Preventative Services Task Force (USPSTF) recommendations on breast cancer screening would be controversial. I tried to discuss these guidelines and the issues involved in a calm and rational way, relatively devoid of Insolence, Respectful or not-so-Respectful, yesterday, pointing out that screening guidelines were clearly due for revision but also recognizing the problems with the USPSTF recommendations and valid criticisms of them. In the end, I concluded that, among the critics, the ASCO discussion of the proposed guidelines…
mikethemadbiologist | November 18, 2009Friday, the NY Times described the relatively paltry efforts in cancer prevention, compared to those for heart disease. Not that researchers haven't been busy figuring out how to prevent various cancers:
Then, in 1999, he had a chance to do another breast cancer prevention trial, this time of an osteoporosis drug, raloxifene, or Evista, which did not have the cancer drug taint. It was to be compared with tamoxifen.
The $110 million study, involving 19,000 women, ended in 2006. The two drugs were found to be equally effective in preventing breast cancer, but with raloxifene there was no…
oracknows | November 18, 2009"Early detection saves lives."
Remember how I started a post a year and a half ago saying just this? I did it because that is the default assumption and has been so for quite a while. It's an eminently reasonable-sounding concept that just makes sense. As I pointed out a year and a half ago, though, the question of the benefits of the early detection of cancer is more complicated than you think. Indeed, I've written several posts since then on the topic of mammography and breast cancer, the most recent of which I posted just last week. As studies have been released and my thinking on…
oracknows | November 16, 2009The New York Times has been periodically running a series about the "40 years' war" on cancer, with most articles by Gina Kolata. I've touched on this series before, liking some parts of it, while others not so much. In particular, I criticized an article one article that I thought to be so misguided about how the NIH grant system leads researchers to "play it safe" and how we could cure cancer if we could just fund "riskier" research that I had to write an extended screed about the misconceptions in the article. The latest installment, Medicines to Deter Some Cancers Are Not Taken, also by…
terrasig | November 15, 2009
On Friday, I wrote a post about the 20th anniversary of my PhD dissertation defense and my reverence for Henrietta Lacks, the woman whose cervical cancer gave rise to the first immortalized human cell line and the primary system for my work. I also alluded to The Immortal Life of Henrietta Lacks, the upcoming book by Rebecca Skloot that is already garnering extensive pre-release praise.
I was, as readers have come to expect, quite a bit sentimental and reflective, with a call that we all do our part to somehow acknowledge those patients whose tissues make it possible for us scientists to do…
terrasig | November 13, 2009Twenty years ago this morning, I had to defend a body of work that contained this paragraph on page 24:
HeLa cells are a human cervical carcinoma cell line having a doubling time of 24 hr and were obtained from Dr. Bert Flanegan, Dept. of Immunology and Microbiology, University of Florida. HeLa cells were maintained as subconfluent monolayer cultures in minimal essential media (alpha modification; GIBCO) with 10% fetal bovine serum (GIBCO) at 37° under a humidified atmosphere containing 5% CO2. Cells were maintained in logarithmic growth by subculturing every other day using 0.05% trypsin/0.…
oracknows | November 10, 2009Here we go again.
I see that the kerfuffle over screening for cancer has erupted again to the point where it's found its way out of the rarified air of specialty journals to general medical journals and hence into the mainstream press. This is something that seems to pop up every so often, much to the consternation of lay people and primary care doctors alike, often trumpeted with breathless headlines along the lines of "What if everything you knew about screening was wrong?
It isn't, but some of it may be. The problem is the shaking out process. I'll try to explain.
Over the last couple of…
oracknows | November 9, 2009
This project is behind schedule. The reasons, I hope, are forgivable. First off, there was just too much other stuff going on last week, to the point where, even though I've read several chapters of Suzanne Somers' new book (if you can call it that) Knockout: Interviews with Doctors Who Are Curing Cancer--And How to Prevent Getting It in the First Place (Random House website), I couldn't force myself to sit down in front of the computer, copy of Knockout in front of me in order to pick choice brain-necrosing quotes from. Besides, the whole issue of Desiree Jennings came up, as well as a…
terrasig | November 9, 2009Hella HeLa!
Skloot is PWned, as it were.
I learned late last night that author Rebecca Skloot was to be featured on the cover of this week's issue of Publishers Weekly. So, I clicked on the site this morning before the coffee was even done brewing and there is our wordsmithing hero.
I know that "The Making of a Bestseller 2010" is sure to make any author nervous but my reading of the manuscript tells me that the prediction is entirely consistent with the work.
Regular readers will know that we featured Ms Skloot here last week to brainstorm about her upcoming, self-supported book tour…
oracknows | November 5, 2009Over the last week or so, I've been confronted full bore with cranks, staring down the barrel, if you will, of a crank shotgun, one barrel being the anti-vaccine movement in general (with J.B. Handley and his misogyny being the buckshot, so to speak) and the other being Suzanne Somers and her despicable cancer quackery. Indeed, over the last five years, I've subjected myself to some of the most outrageous bits of unreason, conspiracy mongering, and pseudoscience. Be it the anti-vaccine movement, quacks, 9/11 Truthers, Holocaust deniers, creationists, or any of a variety of other bits of…
terrasig | November 5, 2009
Some readers may be aware that Rebecca Skloot is about to release her much-anticipated book, The Immortal Life of Henrietta Lacks, a story that is about much more than the black Southern woman whose cervical cancer gave rise to the most famous human cancer cell line. (Crown, 2 Feb 2010, preorder here).
HeLa cells, as they are known, have played a role in the development of vaccines for polio and cervical cancer, the part of last year's Nobel Prize in Physiology or Medicine to Harald zur Hausen, and the PhD thesis 20 years ago of a certain natural products pharmacology blogger.
Having been…
kthompson | November 3, 2009
Sketch by Peter Gulsvig, renowned Zartist
While I believe this bit of news has been well circulated this week, I wanted to give it the Zooillogix bump. Plus, I can only assume Zooillogix readers look to our blog for the latest breaking news... thus it would be a great disservice to all 25 of them to leave this unreported. University of Rochester biologists think they've figured out why the beloved naked mole rat continues to live their entire 30 year moley lifespans without ever having a tumor. That's right. No researcher has ever discovered evidence of cancer in these beauts.
The biologists…
oracknows | November 3, 2009Be afraid. Be very, very afraid. After a prolonged wait, it's finally here:
Yes, my promotional copy of Suzanne Somers new book Knockout: Interviews with Doctors Who Are Curing Cancer--And How to Prevent Getting It in the First Place. (The Dalek was included because, well, I was just feeling perverse when I took this picture.)
I can only say that, after having perused the next couple of chapters after Chapter 1, I can already feel my brain melting and oozing out through my ears, screaming as the neuron-necrosing stupidity liquifies it. I've also noticed that, by and large, this book is…
oracknows | October 27, 2009
About a month and half ago, we learned that über-quack Hulda Clark, the woman who said that she had the Cure for All Cancers, had died on September 3, 2009. I was criticized for entitling my post Requiem for a Quack, but, given how Clark's quackery had contributed to the suffering and deaths of an unknown number of cancer patients, I didn't really feel too bad about it, although I do realize that the taboo about speaking ill of the recently dead is a strong one.
At the time, I was curious what the cause of Dr. Clark's death was, because it seemed rather mysterious, being described as the…
oracknows | October 22, 2009I hadn't planned on writing about Suzanne Somers again so soon. After all, I haven't yet received the promotional copy of her book (Knockout: Interviews with Doctors Who Are Curing Cancer--And How to Prevent Getting It in the First Place) that a most generous reader has sent to me, and I didn't think I'd have a chance until a few days after the book arrived. However, something's been bothering me since yesterday's post, and it's bothering me enough that I think it deserves a followup post of its own. I alluded to it briefly during part of my post, but I really think it's something to be…
oracknows | October 22, 2009Apparently, some of my readers in Canada are getting this when they look at any of my Suzanne Somers posts:
No other country seems to be affected; at least, no readers from other countries have reported the problem to me.
This will not do. The Overlords have been informed. In the meantime, if you are in Canada, I apologize. Ads for such rank quackery and misinformation have no more place on ScienceBlogs than the creationist ads that popped up a while ago. Fortunately, from my locale, I have not been able to replicate the problem. However, if you are in a country other than Canada and see…