Criminal behavior

Asking for a friend... But seriously, this is a real question. For example, several years ago, Herbert Weinstein tossed his wife out the window of their Manhattan apartment, after killing her, following an argument. He was well known to be a non violent person, and there was really no good reason for him to murder his wife this way. But, it turns out, his prefrontal cortical region was compromised by a very large cyst. Weinstein was one of the first in recent decades to use an insanity style defense connected to neuro-imaging or other neurobiology showing a demonstrable, physical, brain…