epidemiology
tsmith | April 25, 2011Just received an email from Vector-Borne and Zoonotic Diseases saying that my recent article, The Emergence of Staphylococcus aureus ST398, will be available for free online for the next two weeks. It was submitted roughly a year ago so it's already a bit dated in this quick-moving field, but provides an overview of "livestock-associated" MRSA up to mid-2010 or so--including food-associated MRSA.
tsmith | March 24, 2011Over at the Worms and Germs blog, Scott Weese has a great post on MRSA testing. He notes the he's frequently asked by human MRSA patients whether their pet should be tested as well, since several studies have documented transmission of MRSA between humans and their companion animals. His first response is always, "why?"
One big question I ask is 'why do you want to know and what would you do with the results?' Sometimes people want to know their pet's status to see if the pet was the source of their infection. However, MRSA in pets is typically human-associated, and if a pet is carrying…
lborkowski | December 15, 2010The Pittsburgh Post-Gazette is running a fascinating in-depth series on air pollution in Western Pennsylvania. While it's got a local focus, I'm sure people from other regions can identify with some of the problems it highlights, like the difficulties in regulating pollution that easily crosses state lines and the frustration of seeing inadequate Clean Air Act enforcement.
The series also delves into issues of epidemiology. In the introductory article, Region at risk: Can higher rates of death be linked to air pollution?, Don Hopey and Devid Templeton explain that the Post-Gazette analyzed…
gregladen | September 16, 2010Editor's Selection IconThe other day a friend of mine bumped into some news that concerned her. She could have asked a random person about this to find out more information, but there was a bit of information that came with the news indicating that I might know more than the average person about it. So, she asked me, and as it turns out, I did not know anything. But, having heard the news from her, I noticed a different bit of information that came along with it that told me exactly who would know everything about it, so I sent along a question .... "What's going on with the [deleted]?" I…
tsmith | September 16, 2010Interesting discussion over at The Spandrel Shop and Cackle of Rad on doing field work in the sciences--and the potential dangers that might be encountered. Now, Prof-like Substance and Cackle of Rad are discussing field work along the lines of biological sample collection, sometimes in the middle of nowhere, which isn't something I've ever done. However, we have our own issues when carrying out our epidemiological field sampling; more after the jump.
For new readers, my lab works on emerging infectious diseases, and zoonotic diseases (which can pass between animals and humans) in particular…
sschoenbaum | July 9, 2010In this post I want to address disease control opportunities for EIS officers, many of which are detailed in "Inside the Outbreaks: One of the first things we learned about on joining the EIS was John Snow's determination that an outbreak of cholera in London was attributable to contamination of the water from the Broad St. pump and his stopping the epidemic by removing the pump handle. On reading "Inside the Outbreaks" one is struck with the number of EIS officers whose efforts have removed pump handles....
The efforts of Jeff Koplan, subsequently director of CDC, and Mark Rosenberg,…
sb admin | July 8, 2010Mark Pendergrast writes: Instead of responding to last week's commentaries on this book club blog about my book, Inside the Outbreaks, I want to throw out a controversial idea that runs counter to what many public health commentators apparently believe. So I expect some disagreement here. (I will post responses to the commentaries as "comments" on each commentary. So go back and take a look at what I wrote there, please.)
Fears of bioterrorism are overblown. We should be spending much more money, time, effort, and print (including e-print) on naturally occurring outbreaks, epidemics,…
mpendergrast | July 8, 2010Mark Pendergrast writes: Instead of responding to last week's commentaries on this book club blog about my book, Inside the Outbreaks, I want to throw out a controversial idea that runs counter to what many public health commentators apparently believe. So I expect some disagreement here. (I will post responses to the commentaries as "comments" on each commentary. So go back and take a look at what I wrote there, please.)
Fears of bioterrorism are overblown. We should be spending much more money, time, effort, and print (including e-print) on naturally occurring outbreaks, epidemics,…
sb admin | July 7, 2010Karen Starko writes: Several basic questions related to Reye's syndrome (RS) have come to me from readers of Mark's book, Inside the Outbreaks. These show the importance of continued education on health issues. (For example, some physicians thought that fever was essential to getting RS). Again, thanks to Mark Pendergrast for a wonderful addition to our public health knowledge.
Is an influenza or chickenpox infection necessary to acquire RS?
The answer is no. RS generally has two phases: the antecedent illness and usually, within a few days of this, the syndrome of vomiting and…
sb admin | July 6, 2010Liz Borkowski writes: I wrote last week about how federal agencies can solve the problems that create conditions for disease outbreaks - or fail to solve them, as is too often the case. This week, I wanted to focus on the role Congress plays in public health agencies' effectiveness, because that's another angle that crops up repeatedly in Inside the Outbreaks.
Congress's creation of federal agencies is clearly a huge achievement, and they've also periodically given new powers to already existing agencies. For instance, Mark Pendergrast tells the story of the Dalkon Shield, an IUD that turned…
sschoenbaum | July 2, 2010Steve Schoenbaum writes: In his blog this week, Mark Pendergrast challenges someone/anyone to take on explaining the differences between case-control studies vs. cohort studies. As an EIS officer, back in late May/early June 1968, I did a case-control study as part of the investigation of a common source outbreak of hepatitis in Ogemaw County, Michigan, so I will try to pick up the challenge. I believe it was only the second time case-control methods were used in a CDC epidemic investigation. In using this method I learned about the power of comparison, not just that numerators need…
sb admin | July 2, 2010Steve Schoenbaum writes: In his blog this week, Mark Pendergrast challenges someone/anyone to take on explaining the differences between case-control studies vs. cohort studies. As an EIS officer, back in late May/early June 1968, I did a case-control study as part of the investigation of a common source outbreak of hepatitis in Ogemaw County, Michigan, so I will try to pick up the challenge. I believe it was only the second time case-control methods were used in a CDC epidemic investigation. In using this method I learned about the power of comparison, not just that numerators need…
grrlscientist | July 1, 2010tags: vultures, Gyps species, conservation biology, endangered species, veterinary medicine, toxicology, physiology, evolutionary biology, pharmaceutical chemistry, epidemiology, mathematical modeling, researchblogging.org,peer-reviewed research, journal club
Only thirty years ago, tens of millions of White-rumped Vultures, Gyps bengalensis,
were flying the skies of Asia. They are now classified as Critically Endangered.
Image: Marek Jobda / rarebirdsyearbook.com [larger view]
A zombie is another name for The Walking Dead -- those who are lifeless, apathetic, or totally lacking in…
lborkowski | July 1, 2010It's Zombie Day on ScienceBlogs! Scicurious at Neurotopia kicked things off, and Joseph of Ataraxia Theatre (whose other projects include the GearHead roleplaying game) provided the cool zombie illustrations.
Thanks to the DC Department of Health's excellent disease surveillance system, a recent outbreak of zombies in the nation's capital was detected quickly enough to allow for capture and isolation of all cases, and no further transmission of the zombie virus has been observed. All state and local health and law enforcement departments have been alerted to the outbreak and instructed on…
grrlscientist | July 1, 2010tags: Following The Mercury Trail, health, environment, ecology, pollution, PCBs, DDT, heavy metals, red tide, human sewage pollution, Stephen Palumbi, TEDTalks, TED Talks, streaming video
There's a tight and surprising link between the ocean's health and ours, says marine biologist Stephen Palumbi. He shows how toxins at the bottom of the ocean food chain find their way into our bodies, with a shocking story of toxic contamination from a Japanese fish market. His work points a way forward for saving the oceans' health -- and humanity's.
TEDTalks is a daily video podcast of the best talks…
sb admin | June 30, 2010Karen Starko writes: When the "financial crisis" started and the news media started throwing around numbers in the trillions and projected fixes in the billions, I realized I just didn't get it. So I got a little yellow post-it, labeled it "understanding trillions," and started a list of examples. And when I learned that the US GDP in 2006 was 13T and the derivative market, estimated in June 2007, was valued at 500T, I quickly got a sense of the potential drain of the derivative market (in which money is spent on items without real value...my definition, please correct me if I am wrong). I…
sb admin | June 29, 2010Liz Borkowski writes: Mark Pendergrast wrote yesterday about how politics plays into the work of the EIS, and it's something that I kept noticing as I read Inside the Outbreaks. As he points out, my post last week highlighted the solution to the Reye's Syndrome puzzle - which was solved by Karen Starko, who's also one of the Book Club bloggers! - but didn't get into the larger issue: there can be a big difference between solving the puzzle and solving the problem. In yesterday's post, Mark writes:
Although Karen's and subsequent CDC studies clearly demonstrated that giving children aspirin…
sb admin | June 28, 2010Mark Pendergrast writes: Thanks to commentators Liz Borkowski, Karen Starko, Steve Schoenbaum, and Mark Rosenberg for their thoughtful posts, though it appears that Mark Rosenberg's post got cut off after his first-paragraph query asking why anyone would go into the field of public health. I will wait to respond to his post once I see him answer his own question! In the meantime, there is much to talk about. I (Mark Pendergrast) will respond to parts of what Liz, Karen, and Steve wrote in order, along with other blogger comments.
Let me respond first to a blog comment from John Willis, who…
mpendergrast | June 28, 2010Mark Pendergrast writes: Thanks to commentators Liz Borkowski, Karen Starko, Steve Schoenbaum, and Mark Rosenberg for their thoughtful posts, though it appears that Mark Rosenberg's post got cut off after his first-paragraph query asking why anyone would go into the field of public health. I will wait to respond to his post once I see him answer his own question! In the meantime, there is much to talk about. I (Mark Pendergrast) will respond to parts of what Liz, Karen, and Steve wrote in order, along with other blogger comments.
Let me respond first to a blog comment from John Willis, who…
sschoenbaum | June 24, 2010Steve Schoenbaum writes: "Inside the Outbreaks", Mark Pendergrast's wonderful history of the Centers for Disease Control's Epidemic Intelligence Service (EIS), can be read on many levels. I confess that as a former EIS officer (1967-1969), personally familiar with most of the "elite medical detectives" of the first few decades, I tended to read it "between the lines". I found myself recalling many personal incidents, interactions with others, and themes mentioned but not necessarily fully developed in the book. I'd like to consider a couple of those here:
Early on in "Inside the Outbreaks…