Hair Color

In the aughts the elucidation of human pigmentation genetics was of one the major successes of 'omic' techniques. The fact that humans exhibit some continuous variation in complexion was strongly suggestive that more than one gene was at work to generate the range of the phenotype. On the other hand pedigree based studies going back to the 1960s suggested that only a modest number of large effect genetic variants were producing the variance. Today we can say with reasonable certainty that about half a dozen genes account for almost all the between population variation in pigmentation. For…

tags: researchblogging.org, premature hair graying, autosomal dominant trait, genetics, horses, hair color, syntaxin-17, melanocortin-1 receptor, cis-acting regulatory mutation, melanoma, evolution This horse is in the process of losing its pigment. It will end up being all white by the time it is eight years old. Image: Horse Wallpaper [larger view]. Even though I have always been a fan of black horses, my heart did leap at the sight of the noble Shadowfax racing towards Gandalf in response to his call in the Lord of the Rings. White horses have symbolized purity throughout most ages…