measles
oracknows | January 30, 2015
Yesterday, I wrote about false balance in reporting on vaccines in the wake of the Disneyland measles outbreak. For those who've never encountered this blog, what I mean by false balance is when journalists, in a misguided belief that there are "two sides" (i.e., an actual scientific controversy) about the safety of childhood vaccines and whether they cause autism and all the other ills blamed on them by antivaccinationists or not, interview an antivaccine activist, advocate, or sympathizer for "balance" and to "show both sides of the story." The problem with that technique, so deeply…
oracknows | January 29, 2015
Imagine, if you will, a time machine capsule going all the way back to the earliest days of this blog, back in 2005 and 2006. Now consider the antivaccine movement, which somehow I became very interested in very early, an interest that continues to this day. Do you remember one theme that I kept hitting again and again? Besides the pseudoscientific quackery often promoted by antivaccinationists, that is? That theme was false balance. Back when I first started blogging, no matter what the angle of the story, when the press reported about the topic of vaccines—or the topic of autism, for…
oracknows | January 27, 2015
Here we are, into a new week, and the Disneyland measles outbreak continues to grow, the total number of cases now having topped 100 and the disease attributed to someone visiting Disneyland now having reached my state. More than ever, given the high proportion of victims who weren't vaccinated, antivaccinationists are feeling the heat. Rober, "Dr. Bob" Sears, MD might have been the most petulant one trying to downplay the seriousness of measles and then letting out a whole bunch of antivaccine dog whistles to his patients to let them know that, despite his assertion that the measles vaccine…
oracknows | January 21, 2015
In the wake of antivaccine-pandering pediatrician "Dr. Bob" Sears' attempt to paint the measles as no big deal, so much so that it totally escaped his notice that it might not be a bad idea to recommend that the unvaccinated get the MMR vaccine in the midst of an outbreak, the bad news about the Disneyland measles outbreak just keeps coming in. Hot off the presses yesterday:
There are now 67 confirmed cases of measles in an outbreak centered in California, health officials said.
The California Department of Public Health said there are now 59 cases in the state – 42 that have been directly…
oracknows | January 21, 2015
Poor, poor, pitiful Dr. Bob.
For those of you not familiar with him, I'm referring, of course, to Robert "Dr. Bob" Sears, MD, the antivaccine-sympathetic (or, more appropriately, antivaccine-pandering) pediatrician in Capistrano Beach, CA (between Los Angeles and San Diego in Orange County) known for his Vaccine Book, a veritable font of antivaccine misinformation gussied up as a "reasonable" middle ground. Too bad it's not.
In any case, in the wake of the Disneyland measles outbreak, Dr. Bob has found himself under a lot of criticism, along with our "good buddy," the other famous…
tsmith | January 15, 2015Measles has come to the happiest place on Earth. As of this writing, a total of 32 cases of measles have been linked to Disneyland visits that took place between December 17th and 20th. About 75% of the cases identified to date were not vaccinated, either because they chose to forgo vaccines or because they were too young, and at least 6 have been hospitalized.
A measles outbreak is a public health disaster, which can cost into the millions of dollars in health resources. You can be sure that public health workers in California and beyond are working overtime trying to identify cases, educate…
oracknows | December 10, 2014
One aspect of my life that's kind of strange is how I've basically ended up back where I started. I was born and raised in southeast Michigan (born in the city of Detroit, actually, although my parents moved to the suburbs when I was 10). After going to college and medical school at the University of Michigan, I matched at a residency in Cleveland (regular readers know that it was Case Western Reserve University), and then did a fellowship in surgical oncology at the University of Chicago. Finally, I ended up taking my first "real" (i.e., faculty) job at the Cancer Institute of New Jersey…
lborkowski | November 5, 2014Best American Science and Nature Writing 2014, edited by Pulitzer-winning writer and professor Deborah Blum, features two pieces that remind us how public-health interventions can become less effective if we as a society don't use them appropriately -- and, based on the spelling of the authors' last names, they're right next to each other in the anthology. Maryn McKenna's "Imaging the Post-Antibiotics Futre," published in Medium, and Seth Mnookin's "The Return of Measles" from the Boston Globe Magazine warn that diseases we thought we'd conquered could easily return and become major killers…
oracknows | July 6, 2014Lawrence Solomon appears to be a rising star in the antivaccine movement. I started taking notice of him a couple of months ago, spewing classic long-refuted antivaccine talking points with the enthusiasm of a newbie who thinks he’s the first one to have thought of them and the arrogance of ignorance of a convert who has no clue that he’s spewing complete and total bollocks. Lately, he’s been spewing that bollocks in various places, including his own website, the Financial Post, that wretched hive of antivaccine scum and quackery, The Huffington Post (a.k.a. HuffPost), and, a week ago, The…
milhayser | June 13, 2014When a parent chooses not to vaccinate their child, they put many other people at risk. Some infants cannot be vaccinated due to medical complications, and even fully-vaccinated people are not always fully protected. Jessica Parsons tells the story of baby Finn on Aetiology, who was diagnosed with Ewing’s Sarcoma at the age of 3 months and has been undergoing chemotherapy, surgery, and blood transfusions ever since. Because he was immunosuppressed, Finn could not be vaccinated, and despite responding well to cancer treatments, his life was imperiled by a case of whooping cough. Meanwhile, on…
sa smith | May 27, 2014The MMR vaccine does not cause autism. The guy who initially made that claim made it all up, and literally no one since has found any evidence to support that claim.
We have known this for quite a while now, and yet, the anti-MMR fad is still going, and parents arent vaccinating their kids. And its the *kids* who suffer from their parents poor decisions.
So what are scientists and physicians to do? How can we get the message across to anti-vax parents?
Effective Messages in Vaccine Promotion: A Randomized Trial
Researchers in this paper tried four approaches to educate/get parents to agree to…
sa smith | May 16, 2014So scientists cured a woman of a pervasive, treatment resistant multiple myeloma.
With a genetically modified, vaccine strain measles virus.
Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy
*anti-vax-anti-GMOers-heads-explode*
The media is going nuts over this, but this is not a new idea/approach. Measles, and certain other viruses, can be domesticated and modified to kill cancers-- we call them oncolytic viruses.
Sometimes we straight-up genetically modify viruses for the explicit purpose of attacking a cancer. We have done this with Newcastle virus vs prostate cancer,…
oracknows | May 7, 2014If there's a story I neglected to mention last week that I should have, it's that Andrew Wakefield is being a bully again, trying to use legal intimidation to silence his critics, namely Forbes.com blogger Emily Willingham. Of course, Wakefield has done this so many times that the fact that he's done it once again is hardly newsworthy, but that never stopped me before, because it's important to document the pattern of legal harassment. The timing was bad. The antivaccine crank blog Age of Autism posted a copy of Wakefield's letter after I had already finished Friday's post, and by the time…
sa smith | April 29, 2014If we vaccinated everyone who could be medically vaccinated against measles, measles would be eradicated.
Though there are other measles-like viruses, humans are the only hosts for what we commonly refer to as 'measles'.
Use vaccines to cut humans out of the equation? Extinct virus.
Its that 'easy'.
Unfortunately, measles 'wants' to exist, and they have human hosts, anti-vaxers, to help it stay alive.
Wat do?
Invent a shelf-stable oral drug that slows down measles infections, thats wat do:
An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus…
sa smith | April 23, 2014Spoiler to apologize for click-bait title:
Yes, the MMR vaccine works just fine.
But there is a difference between 'just fine' and 'perfectly'.
A few things I would want in a 'perfect' vaccine-- Only one dose is needed, zero side-effects, 100% protective antibody or CTL mediated immunity for life, inability of the target pathogen to evolve resistance to the vaccine, dirt cheap, can be stored at room temperature (but stable at high/low ambient temperatures), doesnt need to be administered with a needle-- Im sure you and I can think of a lot more.
But we dont live in a world where 'perfect'…
gregladen | April 6, 2014I just watched a report on ABC news about anti-vaxers causing the current and alarming measles outbreak. It was a reasonable report for MSM though I missed large parts of it because I was multitasking ineffectively. But an idea came to me that would go a long way to manage this problem of anti-vaxers threatening everyone else's health and well being. Lives, even. They are threatening our lives.
Here's the deal. Most public schools have a mealy-mouthed policy that allows people to send their kids to school unvaccinated because they are dumb asses. That's a problem and that should be…
oracknows | March 31, 2014As hard as it is to believe, I've actually "known" pediatrician to the antivaccine stars (such as Jenny McCarthy), "Dr. Jay" Gordon, for nearly nine years now. It began back in 2005 when I first noticed him writing blogs full of antivaccine nonsense at the then-new group blog, The Huffington Post, where I noted antivaccine rhetoric running rampant, complete with amazing examples of what I like to call the "pharma shill" gambit. Since then, he's periodically come to my attention, be it for nonsense equating vaccine manufacturers to tobacco companies, falling headlong for the bogus "toxins"…
oracknows | March 28, 2014Dr. Robert Sears has to be one of the most irresponsible pediatricians on the face of the earth, if not the most irresponsible. Many of you might recall that a little more than a week ago "Dr. Bob" posted a borderline unhinged rant on Facebook aimed at his own patients, who, quite reasonably, were calling him about the measles outbreak going on in southern California right now and asking him about the measles vaccine. It was entitled Measles Epidemic . . . NOT!, and his response boiled down to, in essence, "get the vaccine if you're worried, but there's no real reason to worry." He also…
tsmith | March 13, 2014Being a new parent is exhausting. All of a sudden, you're out of the hospital and on your own with this amazing, tiny human, and you alone are responsible for her care. You're given reams of paperwork about feeding and sleeping, developmental milestones, red flags to look out for. You're inundated with information you barely have time to look at. Mom is trying to heal from childbirth while barely sleeping, while her partner is trying to pick up the slack and pitch in as much as possible. You both fumble with the car seat, thinking that NASA must have equipment that's easier to figure out. You…
dr. dolittle | August 29, 2013A virus is to blame for the deaths of hundreds of bottlenose dolphins along the East Coast of the United States: