PharmKid BlogFodder

Quick question for readers who conduct research with vertebrate animals. We were gazing lovingly at the PharmBeagle this morning and got into a discussion that the beagle is on one of the primary model species for long-term toxicology studies required of drug companies by the US Food and Drug Administration. Is there a comparative pharm/tox reason why do we not use squirrels, the arch enemy of the beagle?
The US Food and Drug Administration is usually the first federal authority to take action on adverse event reports for any health product. But few appreciate that the FDA is also responsible for regulation of cosmetic products: pretty much anything applied to the skin. So, it was no surprise when I was trolling the FDA adverse event reports and news releases to find their announcement of a recall of a number of children's face paints due to rashes and undue skin irritation. The products are manufactured by Shanghai Color Art Stationery Company Limited, Shanghai, China. The original recall…
...it must be Spring in the Northern Hemisphere (7:44 am EDT)
The childlike wonder, creativity, observations and questioning are all qualities that we scientists try to bring to our research and teaching. The observations of a child may seem insignificant to some but I am amazed when PharmKid comes up with questions or associations that I cannot explain. I don't blog about this much unless it has something to do with scientific queries, such as our top-traffic answer and follow-up to her question about where helium comes from. The latest question was fed by us recently adopting a dog and driving past a Veterans Administration Medical Center. I tried…
Sci/Med blogging is an interesting pastime. You can spend a tremendous amount of time writing a post and get two comments and 30 total viewers, or you can write a brief post about your daughter asking where helium comes from and get many more commenters and nearly a thousand viewers. Clearly, the five-year-old is a better source for blog content. Q.E.D. And, wow, what we have learned from our readers in response: one frequent Australian commenter, Chris Noble, confirmed the abundance of helium in Amarillo by noting their next shipment was indeed coming from Texas. Casey pointed us to an…
So, PharmK'er and I were at the originator of the chicken sandwich and she wanted a balloon. She then asked why said balloon was floating. Dad was safe in explaining how helium is lighter than the nitrogen-oxygen-carbon dioxide mixture we breathe. Then came the killer: "Daddy, where does the helium come from to fill the balloons?" "A compressed gas cylinder" was not the answer she was looking for. Thankfully, PharmMom, MD, consulted "the great big book of everything." Commercial helium is fractionated from natural gas, where it comprises about 7-8% of its volume, particularly in deposits…