propranolol

Have you ever taken one of the now-over-the-counter heartburn relief remedies like Tagamet, Zantac, or Pepcid? How about the beta-blocker atenolol (Tenormin) or metoprolol (Lopressor) for antihypertensive therapy, or the original less-selective beta-blocker propranolol (Inderal) for migraines, presentation anxiety or stage fright? If you answered yes to either question, you owe a debt of gratitude to Sir James Black, the Scottish physician who left us earlier this week at age 85. The best obituary I have seen memorializing Sir James comes from the UK Telegraph. Black was called the father…
A couple of weeks ago, I wrote about propranolol, a drug that can erase the emotion of fearful memories.  When volunteers take the drug before recalling a scary memory about a spider, it dulled the emotional sting of future recollections. It's not, however, a mind-wiping pill in the traditional science-fiction sense, and it can't erase memories as was so widely reported by the hysterical mainstream media. The research that's published today is a different story. Jin-Hee Han from the University of Toronto has indeed found a way to erase a specific fearful memory, but despite the superficial…
The mainstream media are just queuing up to fail in their reporting of the propranolol story from a couple of days ago. To reiterate: Propranolol is commonly used to treat high blood pressure and prevent migraines in children. But Merel Kindt and colleagues from the University of Amsterdam have found that it can do much more. By giving it to people before they recalled a scary memory about a spider, they could erase the fearful response it triggered. The critical thing about the study is that the entire memory hadn't been erased in a typical sci-fi way. Kindt had trained the volunteers…
The wiping of unwanted memories is a common staple of science-fiction and if you believe this weekend's headlines, you might think that the prospect has just become a reality. The Press Association said that a "drug helps erase fearful memories", while the ever-hyperbolic Daily Mail talked about a "pill to erase bad memories". The comparisons to The Eternal Sunshine of the Spotless Mind were inevitable, but the actual study, while fascinating and important, isn't quite the mind-wiper these headlines might have you believe. The drug in question is propranolol, commonly used to treat high…