wyss

Most synthetic biologists and biological engineers (and basically everyone else) think of DNA as code, simply carrying the information to make the RNA and proteins that do the real work inside the cell. In the past few years, a small group of biological engineers have used DNA instead as a physical substrate, a programmable nanomaterial to build all kinds of tiny shapes with (even smiley faces). The shapes that the DNA folds into depend on the sequence, which controls how different strands match up to each other and bend. For a great introduction to building shapes out of DNA in 2D and 3D…