Sorry, posts will be few and far between. I need to do some experiments.
Here's a nice giant cell with gobs of ER.
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I have a second to blog - forgive me if it's full of typos (chances are, if you read this blog on a regular basis you're use to them) but it has been a while and I need to get back into the swing of things.
Last week, Jonathan Weissman came over to Harvard Medical School. I had the opportunity not…
Just a quick lab advertisement, my bay mate Yoko and my boss Tom have a review article in Cell about how morphological differences between various regions of the endoplasmic reticulum (ER) are representative of functional differences.
You can divide the ER into 3 morphological parts.
- The Nuclear…
Sorry, I haven't been writing much in the past few days.
Here are some cool ER papers I've seen recently:
Direct membrane protein-DNA interactions required early in nuclear envelope assembly Sebastian Ulbert, Melpomeni Platani, Stephanie Boue, and Iain W. Mattaj JCB (2006) 173:469-476
When the…
I finally got off of my butt and read the latest paper from the Hegde group at the NIH. They answered a fundamental problem in membrane biology: how do you insert tail-anchored proteins into the membrane.
When proteins are synthesized, any newly made signal sequence or transmembrane domain that…