An so proceed ad infinitum

The vermin only teaze and pinch
Their foes superior by an inch.
So, naturalists observe, a flea
Has smaller fleas that on him prey;
And these have smaller still to bite 'em,
And so proceed ad infinitum*:
-Jonathan Swift

Even though I study the immune system, it always amazes me just how many creatures make their living by parasitizing other creatures. It's like the food chain turned on its head. The food chain you probably learned about in school says that many organisms feed on other organisms, which get fed on by others until you reach whatever ultimate predator sits at the top of the food chain.

But even the lion can get infested with parasitic worms, or bacterial infections. And those worms and bacteria can get infected with viruses, and they do. Carl Zimmer has a typically great post about the viruses that prey on the bacteria that live in our mouths, and how scientists are beginning to unravel the constant battle that exists in creatures too tiny to be seen.

These microbes live in our guts, lungs, mouths, noses, skin, and many other nooks and crannies. Far from making us sick, they help us in many ways, making food for us, defending us from invaders, and nurturing our immune systems.

These bacteria are also hosts to viruses. In World War I, the Canadian doctor Felix d'Herelle discovered the first virus infecting bacteria while studying the stool of French soldiers sick with dysentery. Once he isolated the bacteria-attacking virus, he could use it to destroy cultures of the dysentery-causing bacteria.

He goes on to describe how scientists are using special DNA elements found in bacteria that have fended off viral attack as a sort of historical record, documenting battles faught over time in the mouths of several individuals. Check it out!

---

*These lines are so burned into the psyche of microbiologists that we almost named this blog "Ad Infinitum."

More like this

The vermin only teaze and pinch Their foes superior by an inch. So, naturalists observe, a flea Has smaller fleas that on him prey; And these have smaller still to bite 'em, And so proceed ad infinitum. Jonathan Swift, "On Poetry: A Rhapsody" There's so much to love about this story from Nature…
It has been suggested that the first posts of this book club be devoted to the Universal Rules of Life. So... What is life? Jessica asks, Carl, twice in the book you refer to viruses as "creatures." Perhaps you used the word metaphorically. In any case I'd love to know whether you think viruses…
A lot of people think of viruses and bacteria in our bodies as nothing more than pests. It's certainly true that a lot of them do an excellent job of making us ill. But some viruses and bacteria merged with our ancestors over the course of billions of years, and if you were to have them removed…
There are two excellent papers in the August edition of Emerging Infectious Diseases (open access) about influenza that suggest alternative (or parallel) ways of dealing with an influenza pandemic (note: by "alternative", I don't mean woo). The standard response that is typically discussed is an…