Live from Seattle: Fatal intracerebral mass bleeding edition

The poster sessions were largely a bust yesterday but I did come across a couple of interesting ones:

1) Definitive evidence that it was the melamine + cyuranic acid that caused toxicity in animals (by creating crystals inside the kidney). As I've noted before, neither is very toxic on it's own. Not a surprise but good to get some confirmation.

2) Ms Vitalone is a woman after my own heart. Her presentation: Natural is not always safe: A lesson from the literature on the use of herbal products. Now, doesn't that sound familiar? It was basically a compilation of what we know about adverse events due to certain herbal supplements. I picked up the reference list, and I just have to share one article title with you:

Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofen.

Yikes!

3) A few posters on acrylamide in food (how much Finns get, how it is absorbed and excreted). I'm even more convinced that this isn't a big problem, and as such will eat something fried today.

More like this

A study this month ($) in Pharmacoepidemiology and Drug Safety (just rolls off the tongue doesn't it?), looked at poison control data during 2001 for two herbal supplements: St. John's wort and Echinacea. There were 356 contacts for SJW and 406 contacts for Echinacea. That's not what interests me;…
Via Terra Sigilatta (who beat me to this one, as I saw the press release yesterday but never got around to blogging about it), we find yet another case of heavy metal contamination of a popular supplement, this time herbal kelp supplements. This discovery was prompted by the investigation of a case…
This morning's post from Molecule of the Day reminds me to ask "cyanuric acid question." With the recent adulterations with melamine of Chinese milk and milk products (like White Rabbit chocolates) and foods with other milk-derived ingredients, we wonder if we will ultimately hear that a compound…
Advocates of so-called "complementary and alternative medicine" (CAM) frequently make the claim that they are the victims of a "double standard," in which (or so they claim) they are subjected to harsher standards than what they often refer to as "conventional" or "orthodox" medicine, usually…

hysterical...i spent several minutes agitating my advisor with an unscheduled rant about the many dangers of 'natural' products and the ridiculous misconception that natural products are not simply benign but always beneficial. he finally just glared at me until i stopped.

and then he reluctantly agreed.

Natural! Just the other day I learned that organic farming likes to use rotenone as a pesticide because it is a natural product. It is also a mitochondrial toxin and has both cellular and epidemiological studies strongly suggesting it is a causative agent in Parkinsons disease. Organic farming also likes to use copper as a fungicide. High copper load, or any heavy metal load for that matter, is also a risk factor for cerebral damage ... .

AS to Ginkgo causing bleeding the data is controversial. The biochemistry (strong inhibitor of platelet activating factor) suggests that should be the case but this has not been substantiated in various studies. Nonetheless I caution people against using GB too consistently.

By John Hasenkam (not verified) on 04 Apr 2008 #permalink