Evolution racin' ahead

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In the May edition of Evolution, Hopi Hoekstra and Jerry Coyne have an interesting commentary, "The Locus of Evolution: Evo Devo and the Genetics of Adaptation." They raise two points about "evo devo" (the fusion of developmental and evolutionary biology) that have always bothered me. From the…
PLoS ONE has recently published a paper entitled "Beyond the Gene" by Evelyn Fox Keller and David Harel, in which the authors take a stab at the long standing question: What is a Gene? Because this is such a big picture question, the appropriate discussion of the paper would involve a synthesis of…
A paper just published online in Nature Genetics describes a brute force approach to finding the genes underlying serious diseases in cases where traditional methods fall flat. While somewhat successful, the study also illustrates the paradoxical challenge of working with large-scale sequencing…
I found a recent paper in Nature fascinating, but why is hard to describe — you need to understand a fair amount of general molecular biology and development to see what's interesting about it. So those of you who already do may be a little bored with this explanation, because I've got to build it…