Antiviral model series
revere | March 21, 2007[A series of posts explaining a paper on the mathematical modeling of the spread of antiviral resistance. Links to other posts in the series by clicking tags, "Math model series" or "Antiviral model series" under Categories, left sidebar. Preliminary post here. Table of contents at end of this post.]
The use of antiviral drugs to prevent or manage a pandemic with influenza/H5N1 is both a mainstay of national and international pandemic plans and a source of controversy. Will there ever be sufficient doses to make a difference? If there were, could they be deployed and administered in time? If…
revere | March 20, 2007Tomorrow we begin a blog experiment, one we already judge has failed. In January Marc Lipsitch and his team at the Harvard School of Public Health published a splendid paper using a mathematical model to investigate the spread of antiviral resistance in the control of pandemic influenza. When we read it our first thought was to write a substantial blog post about the results. The paper was published in PLoS Medicine almost the same week as another mathematical model on spread through the air traffic system by Colizza et al. and the Colizza paper seemed to get most of the newswire notice. But…