The Awesome Power of Natural Products
terrasig | December 14, 2009Last week in Stockholm (and Oslo), the 2009 Nobel Prize winners were gloriously hosted while giving their lectures and receiving their medals and diplomas. In Chemistry this year, the Nobel was shared by Venkatraman Ramakrishnan, Thomas A Steitz, and Ada E Yonath for their studies on the structure and function of the ribosome, a remarkable nucleoprotein complex that catalyzes the rapid, coordinated formation of peptide bonds as instructed by messenger RNA. My post on the day of the announcement in October was designed to counter the inevitable (and now realized) criticisms that the prize was…
terrasig | November 20, 2009
Denise Gellene in the New York Times is reporting this morning that Scottish physician, Sir John Crofton, passed away on 3 November at age 97.
Crofton is best known for implementing a combination drug regimen to treat tuberculosis, the insidious lung infection with Mycobacterium tuberculosis which decimated the US early last century and still kills 2 million a year worldwide. The concept of using drug combinations to increase individual drug potency and slow the emergence of resistance is now a mainstay of therapeutic approaches for cancer, HIV, and other infectious diseases.
Gellene…
terrasig | October 31, 2009This post appeared here originally on 31 October 2007
Have you ever wondered, perhaps on 31 October, why witches are depicted as riding brooms?
The answer is alluded to by Karmen Franklin at Chaotic Utopia in her post as to why witches need to know their plant biology.
The excerpts I'm about to give you come from a superb and accessible pharmacology text entitled, "Murder, Magic, and Medicine," by John Mann, host of the BBC Radio 4 series by the same name.
Witches
"Double, double toil and trouble
Fire burn and cauldron bubble" - Macbeth IV, i
Hallucinogenic compounds called tropane alkaloids…
terrasig | October 7, 2009Welcome visitors coming from a recommendation by Dr Carmen Drahl at C&ENtral Science, the blog of the American Chemical Society's Chemical & Engineering News (C&EN):
Terra Sig has a fantastic post about the chemistry prize. The money quote: "If I see electrons being pushed around, it's chemistry."
Thank you for the kind words, Dr Drahl. New readers, feel free to weigh in down in the comments as to your take on this year's Chemistry prize.
The 2009 Nobel Prize in Chemistry has been awarded to three amazing scientists who elucidated the chemical bond-by-chemical bond action of the…
terrasig | June 30, 2009
I love it when new readers stumble upon old posts.
Such was the case when I received the following delightful comment from Seattle-based psychologist, Dr Gary Grenell, on my April 2008 post about the passing of Dr Charlotte Tan, a pediatric cancer chemotherapy pioneer:
I was probably in one of her earliest actionmycin-D trial groups for Wilms tumor in 1957. Now at age 55, 52 years later, still going strong!
Most of you scientific youngsters today probably only know of actinomycin D as a laboratory tool for inhibiting RNA synthesis. But here in the following repost, learn about the…
terrasig | October 31, 2007Welcome, Reader: This post was updated on Halloween 2009 to remedy linkrot and add an interesting tidbit on the famous Macbeth passage. As it is likely you ended up here via a search engine, click here to go to the updated post.
Have you ever wondered, perhaps on 31 October, why witches are depicted as riding brooms?
The answer is alluded to by Karmen Franklin at Chaotic Utopia in her post as to why witches need to know their plant biology.
The excerpts I'm about to give you come from a superb and accessible pharmacology text entitled, "Murder, Magic, and Medicine," by John Mann, host of…