breast cancer

A recently published case-control study involving more than 2,100 women in southern Ontario, Canada reported a strong association between being employed in the automotive plastics industry and breast cancer. The researchers recruited the 'case' subjects between 2002-2008 among newly diagnosed breast cancer patients and the randomly-selected controls from the same geographic area.  The researchers examined a variety of risk factors for breast cancer (e.g., reproductive history, age) and collected data on the women's employment history.  Elevated odds of breast cancer were found among women…
Another year, another Breast Cancer Awareness Month. While most people who have either been touched by breast cancer or who have a professional interest in it, the significance of Breast Cancer Awareness Month is that it is a time, well, to increase awareness and to promote breast cancer research. There is another side to Breast Cancer Awareness Month, however, and it's not just the question of its excessive commercialization, which concerns some people. Rather, inevitably, just as the vaccine-autism quacks have come out of the woodwork for Autism Awareness Month each April, each October…
For my international readers, it's a holiday here in the U.S. That means I plan on taking it easy, which means I've decided on doing, in essence, a "rerun." I chose this particular rerun based on my post from last Thursday. I thought that rerunning this particular post is a good reminder of what the cost of eschewing science-based therapy for breast cancer can be, and that price is horrible. This particular post dates back to 2006; so, if you haven't been reading the awesomeness that is my blog that long, it's new to you. I'll be back with new Insolence tomorrow. I've written before about how…
[NOTE: Please be sure to read the addendum!] I hate cancer quackery. I know, I know, regular readers probably figured that out by now, and even new readers rarely take more than a couple of weeks to figure it out. That's because cancer quackery is a frequent topic on this blog. One of the most powerful tools of persuasion that cancer quacks employ in promoting their quackery is something I call the cancer cure testimonial. Basically, a cancer cure testimonial is a story of a patient using alternative medicine and "curing" himself of cancer. Such testimonials come from both practitioners and…
One issue that keeps coming up time and time again for me is the issue of screening for cancer. Because I'm primarily a breast cancer surgeon in my clinical life, that means mammography, although many of the same issues come up time and time again in discussions of using prostate-specific antigen (PSA) screening for prostate cancer. Over time, my position regarding how to screen and when to screen has vacillated—er, um, evolved, yeah, that's it—in response to new evidence, although the core, including my conclusion that women should definitely be screened beginning at age 50 and that it's…
I feel dense for not knowing this important public health fact: women with extremely dense breast tissue are at least four times more likely to develop breast cancer. Over the years, I've had my routine screening mammograms with stellar results.  No evidence of cancer in my two mammary glands.  I've heard radiology technicians comment about my dense breasts, but I thought it was an interesting attribute like droopy breast, or perky breasts or double D breasts. In December 2011, just before my 50th birthday, I was overdue for my routine screening mammogram.  I felt a little guilty for putting…
Two examples of why blogs are better than mainstream news coverage, when it comes to confronting reality and doing something about it, one from the climate wars, one from the front lines of women's health. First, Andy Revkin, a former New York Times journalist who still blogs there. He calls out a coal-industry-backed attempt to silence one of the world's leading climatologists as the "Shameful Attack on Free Speech" that it is. By launching a Facebook campaign to convince Pennsylvania State University to cancel a scheduled talk by Michael Mann, the coal interests have indeed shamed…
Two women died of breast cancer yesterday. One was named Kim Tinkham. One was named Elizabeth Edwards. In some ways, these women were similar. True, one was older than the other, but both of them died far sooner than they should have, one at age 53, the other at age 61. Both engaged in activism about breast cancer. Both were ambitious, driven women. Both died in the presence of their friends and family. Both died within hours of each other. Both demonstrated the implacable killer that breast cancer can be. There the similarities end. One of these women (Kim Tinkham), for example, died…
In the wake of the revelation that Kim Tinkham is dying of what was almost certainly metastatic breast cancer to bones, lungs, and liver after having rejected conventional therapy for her disease in favor of Robert O. Young's acid-base woo, Young's response is now (possibly) known. In the comments after part 6 of Young's interview with Kim Tinkham (discussed by me here), a commenter by the 'nym of inhisgrace7 reports: I wanted to find out for myself the truth so I wrote to Dr. Young and here is his response. Kim has always made her own decisions about cancer. Before I met her she had…
(NOTE: The videos of Robert O. Young's interview with Kim Tinkham have been removed, as I predicted in this post that they would be. Fortunately, I downloaded copies before he managed to do that. Part 6 appears to be still there--for now.) (NOTE ADDED 12/7/2010: Kim Tinkham has died of what was almost certainly metastatic breast cancer.) I hate stories like this. I really do. I hate them with a burning passion that makes it hard for me to see straight when I first find out about them. They make me want to grab a shotgun and go looking for the quack responsible. It's a good thing I've never by…
A couple of weeks ago, as Breast Cancer Awareness Week was approaching, I was highly disturbed to see everybody's favorite wretched hive of scum and quackery (The Huffington Post, in case you didn't know) promoting a dubious breast cancer testimonial for quackery. This testimonial, contained in a book entitled You Did What? Saying "No" to Conventional Cancer Treatment and promoted in a HuffPo post by an acupuncturist named One Woman's Story: Saying No to Conventional Cancer Treatment, on the surface sounded as though a woman named Hollie Quinn had eschewed all conventional therapy after being…
October is Breast Cancer Awareness Month, a fact that is hard to escape. It's one of those things that I have mixed feelings about, particularly now that I've had a close relative, namely my mother-in-law, die of breast cancer less than two years ago. On the one hand, the attention that's brought to the cause of breast cancer is helpful for spurring research and donations to support research, as well as promoting screening programs. On the other hand, I do now have a bit of understanding about "pink washing," and some of the whole "pink thing" at times makes me uneasy. Be that as it may, one…
I hate The Huffington Post. I really do. Why, you ask, do I hate HuffPo so? I hate HuffPo so because of its history from the very beginning of its existence of promoting the vilest forms of anti-vaccine quackery and pseudoscience. It's because, over the last couple of years, not content with being the one-stop-shop for all things antivax on the Internet, right up there with Whale.to, Mercola.com, and NaturalNews.com, HuffPo branched out very early into quantum quackery, courtesy of Deepak Chopra. Just search for "Huffington Post" and "Deepak Chopra" on this blog and you'll discover how many…
Let's see. Now that I'm back from Chicago, having recently attended a major cancer meeting, not to mention having already blogged about the meeting, what to do next? Sure, the whole thing about Andrew Wakefield finding himself just one step away from appearing on Jeff Rense's or Alex Jones's radio show was amusing in the extreme to me, and no doubt there will be much more blogging material to mine in that vein, but if you really want to bring home the crazy there's only one place shy of Whale.to to visit. That's right, I'm talking about that wretched hive of medical scum and villainy, Mike…
If there's one thing that has irritated me (one might even say, irritated me enough to start this blog), it's ideology or religion trumping science. Perhaps the most annoying form of this disease is the tendency of the right wing whackosphere to do everything and anything it can to distort and twist science to agree with its ideology, in particular its religion. One area that I used to write about a lot but don't so much anymore (we bloggers have to subspecialize, I guess, and these days my subspecialty is science-based medicine with only the occasional forays against forms of unreason other…
Homeopaths are irritating. They're irritating for a number of reasons. One is their magical thinking, and, make no mistake, their thinking is nothing but pure magic, sympathetic magic to be precise. That's all that the principle of "like cures like" really is at its heart. Normally, that principle states that "like produces like," but homeopathy reverses that principle by saying that, while like produces like at normal concentrations, like reverses like at high dilutions. Somehow the magical process of shaking the remedy very hard between each dilution step (called "succussion") imbues it…
From Monday's issue of The Press in York, England: A breast cancer patient from York says she is "disgusted" by a shortage of the drug she and hundreds of other women rely on to reduce the risk of the disease returning. Mother-of-two Marion Barclay, 45, said the situation became so serious last Friday, she faced the prospect of missing her daily dose of Arimidex tablets. This story is one of several reports on sporadic, worldwide shortages of Arimidex®, the brand of anastrozole sold by AstraZeneca. Anastrozole is a competitive inhibitor of the cytochrome P450 monooxygenase isozyme known as…
(Ten Best of the Decade from Half of the World's Fair) This series began with the kindness of a friend who agreed to let me ask him about his book about Barry Commoner, science, and modern environmentalism. It then spawned a series of 17 interviews with authors of books in science studies, environmental history, the history of science, and all combinations in between. Every one of them was enjoyable to do; every author was generous and insightful. I've been able to use some of these as thumbnail sketches of readings I use in class. In that, they stand as the best example of blogging as a…
Some interesting news about the breast cancer patent lawsuit I wrote about for Slate's Double X Magazine a few months ago:  A federal district court has just agreed to hear the case. When the lawsuit was first filed, many legal experts I talked to said they were sure the case would get thrown out of court for it's unusual approach, namely that it claims that the practice of patenting genes is unconstitutional See my story about the case here. Filings and other documents related to the case available here.  And see below for the full press release about today's news: Court Upholds Right…
Screening for disease, especially cancer, is a real bitch. I was reminded of this by the publication of a study in BMJ the very day of the Science-Based Medicine Conference a week and a half ago. Unfortunately, between The Amaz!ng Meeting and other activities, I was too busy to give this study the attention it deserved last Monday. Given the media coverage of the study, which in essence tried to paint mammography screening for breast cancer as being either useless or doing more harm than good, I thought it was imperative for me still to write about it. Better late than never, and I was…