data analysis
jhalper | October 27, 2015 Metastatic melanoma tumors. Left exhibits low or absent expression of RASA2 and reduced survival, typical of about 35% of patients. The sample on the right exhibits high RASA2 expression and increased survival
Rates of melanoma are increasing, even as the rates of other common cancers are decreasing. According to the Melanoma Research Alliance, it is the most common cancer diagnosis in young adults 25-29 years old in the United States, the second most common cancer in young people 15-29, and its incidence has tripled in the last 30 years.
What are we doing about it? The Weizmann Institute’…
jhalper | July 21, 2014Do you know the real price of a piece of beef? Here is a nice, round number to chew on: The environmental cost of beef is ten times that of dairy, eggs or poultry. This means that if you chose to eat a steak over an omelet, (assuming they have equal amounts of protein) the ecological footprint of your meal will go from a size 5 to a size 50.
Drs. Ron Milo, Gidon Eshel, research students Alon Shepon and Tamar Makov realized that even though we might try to make the right choices in our diets, we’re likely to base them on the pronouncements of experts. The problem is that neither we nor they…
jhalper | June 8, 2014 Convective clouds forming over the Amazon in a blanket smoke. Image: Prof. Ilan Koren
Horse latitudes, doldrums, calms of Cancer and Capricorn: These are all synonymous names for the forsaken regions of the oceans that sailors of previous eras cursed because the winds that once pushed their sails die out there for weeks at a time. (One suggested explanation for the name “horse latitudes” is that some had to throw the horses overboard there when the supplies ran out.) On land, these subtropical belts – around 30-35° north and south of the equator – help form the world’s deserts.
These…
jhalper | September 12, 2012One of our constant themes is the innovative ways that tools and ideas from math and physics can lead to new insights in the life sciences. Take, for example, a recent study produced by a group that included a professor of mathematics, an oncologist who works in pharmaceutical research and has a Ph.D. in mathematics, an electrical engineer and applied mathematician who is doing a postdoc at Harvard Medical School, and physicians in a medical center research lab.
The idea was to create a mathematical model of a medical syndrome – in this case neutropenia, the low counts of the white blood…
jhalper | March 5, 2012What would you say are the strongest three factors associated with the salaries of major-league baseball players? According to a popular, well-established algorithm, the main influential factors are walks, intentional walks and runs batted in.
How much does he earn?
But a paper recently published in Science reports on a new data analysis tool, which is able to find interesting relationships and trends in complex data sets - relationships that are invisible to other types of statistical analyses.
This could be a big deal: Large data sets with thousands of variables are increasingly common in…
rallain | January 30, 2010After judging the science fair last week, I would like to revisit my tips for you the science fair participant.
Warning number 1
Some of the things I say here might go against what your teacher has told you. I am not sure what you should do in this case. Your teacher gives you a grade and I am just some dude on the internet. Proceed at your own risk.
Oh, and maybe you are a teacher. I think that is great that you are seeking more tips for your students. However, note that I have not read any science fair rules. I am merely thinking about science fair projects from a science viewpoint.…
rallain | December 29, 2009This idea comes from my friend Thomas. His son is like mine in that they both think LEGO are awesome, and they are correct. For some reason, Thomas decided to calculate the price per piece of LEGO in each set. To promote repeatability, I decided to do this also. Looking at the catalog at LEGO.com, I can get both the price of each set and how many pieces it has. Just a note, I looked at almost all of the Star Wars LEGO series and some other select themes. I didn't include any sets that had been marked down in price. I will put the first plot on down below, maybe this would be a good…
sciencewoman | July 24, 2009To recap, I'm prepping a new graduate level course on experimental design and data analysis (EDDA) that will serve MS and PhD students from geosciences and civil and environmental engineering. I've been working through the SERC course design tutorial, and so far I've figured out context and constraints, over-arching goals, and ancillary skills goals. It's finally time to add content to my course.
(Note that the material that follows is a bit outliny, because I'm thinking out loud (on blog paper) here and looking for feedback)
First, according to the good folks at SERC, I need to bring it back…
sciencewoman | July 23, 2009Now that things at ScienceBlogs have returned to normal, and I've drawn down my stash of reader emails, it's time to get back to work on my series on course design. For those who haven't been playing along (1.1, 1.2) I'm prepping a new graduate level course on experimental design and data analysis (EDDA) that will serve MS and PhD students from geosciences and civil and environmental engineering. I don't envision this course as a purely statistics course, though EDDA necessarily incorporates statistical concepts and techniques. Similarly, I don't envision this course purely as a proposal…
sciencewoman | July 15, 2009As introduced yesterday, I'm blogging my way through the SERC tutorial on course design, for a new graduate-only course on experimental design and data analysis. Yesterday, I explained the context and constraints on the course, and today I'm mulling on the course goals. I'm supposed to identify 1-3 over-arching goals for the course and 1-2 ancillary skills goals. Below the fold, I'll share my overarching goals and how I got to them. But I'm struggling with the ancillary skills goals, dear readers, and I'd love your help.
Task 1.2c: Set one to three overarching goals for your course.
The SERC…
sciencewoman | July 14, 2009After articulating that my most dire need is to get funded, it may seem disjointed to embark on a series of blog posts about teaching, but there you have it, the life of a professor at a place that requires both research and teaching. I still contend that I will get fired from my job much more quickly for failure to teach a course than failure to get funded, so I must do something about the new preparation I have for the fall.
The new course, "Experimental Design and Data Analysis," is a graduate-only course with only a loose definition in the course catalog. It hasn't been taught for the…
rallain | March 19, 2009I just got back from judging elementary level science fair (this is like kids in 6th grade or something). Here are some quick notes in no particular order.
Please, please do not have a 20 item list of supplies that you used on your board including things like thumb tacks, tape, paper and poster board. And then please do not read this list aloud during your presentation. I know you are nervous, I feel for you. Maybe you are trying to fill up time - maybe you think a long presentation is a good one. However, don't do it. Stick to the important stuff. If you need to fill up space on your…
rallain | February 12, 2009Previously, I talked about science fairs. One of the problems is that students don't really have a good understanding of data analysis. For me, statistical analysis is just something to do with data. It isn't absolutely true. So, it doesn't really matter that students use sophisticated tests on their data. The important point is they use some type of test to compare data.
I just made up some arbitrary data analysis rules. Maybe if students and judges accept something like this, it could really improve science fair projects and judging.
To explain my analysis, I decided to have my own…
rallain | February 10, 2009Last friday I volunteered as a science fair judge. It took half a day, but I did get free food and tons of things to blog about. There are so many things to say about science fairs that I don't really know where to begin. I actually might not even address all the issues. Here is what I would like to talk about (in no particular order):
What is the purpose of a science fair?
How do you win a science fair? Tips.
What about judging? Are the normal methods reliable?
Data Analysis tips for middle schoolers
Creativity vs. the Internet vs. parents.
Social Science Fair posters? Er?
Why…
sporte | February 25, 2008Bora had an enjoyable post yesterday on obsolete lab skills. I can empathize because I have a pretty good collection of obsolete lab skills myself. These days I'm rarely (okay, never) called upon to do rocket immunoelectrophoresis, take blood from a rat's tail, culture tumor cells in the anterior eye chamber of a frog, locate obscure parasites in solutions of liquid nitrogen, or inoculate Kalanchoe leaves with pathogenic bacteria.
(Wow! It sounds like I worked for the three witches in MacBeth! Fire burn and cauldron bubble!)
I don't entirely think that my lab skills are "obsolete." I…
sporte | November 13, 2007For many years, I had my biotech students do projects where each group of students would analyze their own data, in addition to all of the data gathered by the class. I would draw a table on the white board and each group would enter their data. At the end of the class, all the groups would copy all the results into their notebooks, then analyze them in Microsoft Excel.
This worked pretty well, but it wasn't perfect. There were always cases where one group would be really slow, or someone had to leave early, or I needed to use the board and couldn't.
And, this method certainly wouldn't…