epilepsy

When I first started to take an interest in medical marijuana, I was struck by how much it reminded me of herbalism. Although herbalism is scientifically the most plausible of modalities commonly associated with "complementary and alternative medicine" (CAM), the use of herbal medicines still involve a number of problems, the biggest of which is what I like to call either the delivery problem or the bioavailability problem. In brief, herbs, when they work, are adulterated drugs. The active ingredient is often a relatively small, embedded in thousands of other constituents that make up herbs,…
I recently received the following question from a reader based on a prior blog entry on how a medication used to treat epilepsy also helps reverse memory loss with Alzheimer's disease. You can see the original blog here Question: "I find it a little confusing as to how it is possible that this medication can improve brain and memory function but at the same time cause cognitive impairment? Is that not contradictory that the meds are suppose o help the brain but the side effects are related to the brain? Did the research account the facts that humans do not share all the same proteins as mice…
Three months ago, I wrote about how the Cleveland Clinic had recently opened a clinic that dispensed herbal medicine according to traditional Chinese medicine (TCM) practice. As regular readers might expect, I was not particularly impressed or approving of this particular bit of infiltration of quackademic medicine into a major, generally well-respected academic medical center, particularly given some of the amazingly pseudoscientific treatments espoused by the naturopath who was running the clinic. I also pointed out that, although herbalism is the most plausible (or perhaps I should say the…
Credit: Image courtesy of Stanford University Medical Center, from ScienceDaily According to a press release from Stanford University, California sea lions develop epilepsy from exposure to a toxin produced by algae called domoic acid. The animals develop seizures which can result in memory loss, tremors, convulsions and even death. The hippocampal region in the brain of the affected sea lions shows similar damage as humans with epilepsy, with losses of about 50 percent of neurons. Dr. Paul Buckmaster, professor of comparative medicine at Stanford was quoted as saying, "We found there was…
Image from: Alzheimer's Association Researchers Sanchez et al. from the Gladstone Institute, University of California San Franciso and Washington University School of Medicine discovered that an FDA-approved anti-convulsant medication used to treat epilepsy (levetiracetam) can also reverse memory loss in addition to reducing other Alzheimer's related symptoms in a mouse model of the disease. Alzheimer's is currently the most common form of dementia (memory loss) representing 50-80% of cases. It is a disease that worsens over time. Although there are available medications to help slow the…