HPV
oracknows | August 16, 2017Here we go again.
Antivaxers don't like vaccines. This, we know. They blame them for everything from autism to autoimmune diseases to diabetes to sudden infant death syndrome. They even sometimes claim that shaken baby syndrome is a "misdiagnosis" for vaccine injury. However, there are two vaccines that stand out above all as the objects of antivaccine scorn. the first, of course, is the MMR vaccine. That's on Andrew Wakefield., of course, who almost singlehandedly popularized the fear that the MMR vaccine causes autism. The second most hated vaccine (by antivaxers) is Gardasil or Cervarix,…
oracknows | November 18, 2016Of all the vaccines out there, it’s hard for me to decide which among them antivaccine activists fear and detest the most. Sure, there’s the MMR vaccine, the original granddaddy bete noire, demonized so successfully by Andrew Wakefield as causing autism based on some of the flimsiest evidence ever, evidence later shown to be fraudulent. That has to be near the top of the list of any of the vaccines demonized by the antivaccine movement, despite is safety and efficacy. After all, it is the mMR vaccine that people like Del Bigtree, Andrew Wakefield, and Polly Tommey are still flogging as the…
kkrisberg | October 14, 2016Another day, another study on the benefit of vaccines. This time, it’s a study on the economic cost of vaccine-preventable diseases among U.S. adults — a cost that likely surpasses your wildest guesses.
Published this week in Health Affairs, the study found that vaccine-preventable diseases affecting adults cost the American economy $8.95 billion in 2015, with unvaccinated adults accounting for $7.1 billion of that total. To conduct the study, researchers examined the economic burden associated with 10 vaccines that protect against hepatitis A; hepatitis B; shingles (or herpes zoster); human…
oracknows | February 29, 2016Here we go again.
When you've been blogging for over 11 years, particularly when what you blog about is skepticism and science-based medicine, with a special emphasis on taking down quackery (particularly cancer and antivaccine quackery), inevitably you see the same misinformation and lies pop up from time to time. Indeed, those of us in the biz not infrequently refer to such stories as "zombie lies," because no matter how often you think they've been killed they always come back. Personally, I like to refer to them as Jason, Michael Myers, or Freddy Krueger lies (or just slasher or monster…
kkrisberg | February 25, 2016Another day, another study on the potentially life-saving impact of vaccines. This time it’s a new study on the vaccine against human papillomavirus, or HPV, a sexually transmitted disease that can lead to cervical cancer. Earlier this week, researchers announced that since the vaccine came on the scene, rates of HPV among young women in the U.S. have plummeted.
Published in the journal Pediatrics, the study used data from the National Health and Nutrition Examination Survey to analyze HPV prevalence among women ages 14 to 34 in the four years before the HPV vaccine was introduced in 2006 and…
kkrisberg | May 13, 2015In a perfect example of how the Affordable Care Act is broadening access to relatively low-cost and potentially life-saving interventions, a new study finds that the health reform law likely led more than 1 million young women to seek out the human papillomavirus vaccine and protect themselves against cervical cancer.
In a study published this month in Health Affairs, researchers studied the impact of two ACA provisions: one requiring insurance providers to extend dependent coverage through age 26 and another that required insurers to offer a range of preventive services, such as…
kkrisberg | February 13, 2015When the U.S. Food and Drug Administration approved the first vaccine to protect against cancers caused by certain strains of the human papillomavirus, or HPV, public health advocates cheered its arrival and life-saving potential. Unfortunately, the new vaccine quickly became embroiled in a debate over whether immunizing young girls against HPV, a sexually transmitted disease, would lead to risky sexual behavior. A new study, however, finds that the vaccine is not associated with an uptick in STDs — an indicator that HPV immunization does not promote unsafe sex.
To conduct the study, which…
oracknows | April 1, 2014Of all the cranks, quacks, antivaccinationists, and pseudoscientists that I've encountered (and applied a bit of not-so-Respectful Insolence to) over the years, there are a few who belong in the top tier—or, if you prefer, the bottom tier. They stick out in my memory for a variety of reasons, either through their sheer crankitude on a variety of subjects (such as Mike Adams), sheer persistence on one subject (such as Jake Crosby or any of the denizens of the antivaccine crank blogs Age of Autism or The Thinking Moms' Revolution), or fame for promoting quackery (Joe Mercola). One of these…
milhayser | December 16, 2013Katie Couric riled up the internet last week with her uncritical promotion of anti-vaccine viewpoints on her talk show. It was certainly a twist in the professional narrative of a woman who has undergone televised colonoscopy and mammography to promote cancer awareness. That awareness should have been front-and-center in her discussion of HPV vaccines as well, since HPV infection can lead to cancers of anywhere people put their genitals. Instead, Couric featured two mothers convinced that HPV vaccines had caused death and injury, respectively, to their daughters. On Respectful Insolence, Orac…
oracknows | December 10, 2013Vaccines against the human papilloma virus (HPV), such as Gardasil and Cervarix, seem to have a strange power over people who are otherwise reasonable about science and vaccines. For some reason, HPV vaccines seem to have an uncanny ability to turn such people into raging antivaccinationists almost as loony as the merry band of antivaccine loons over at Age of Autism. At the very least, they seem to make seemingly reasonable people susceptible to blandishments and tropes for which they'd normally otherwise never fall. Truly, Gardasil and Cervarix seem to be vaccines that make reasonable…
tsmith | December 4, 2013Regular readers keeping up on infectious disease issues might have seen Seth Mnookin's post yesterday, warning of an upcoming episode of the Katie Couric show focusing on the HPV vaccine. Even though Mnookin previously spoke with a producer at length regarding this topic, the promo for the show certainly did not look promising:
"The HPV vaccine is considered a life-saving cancer preventer … but is it a potentially deadly dose for girls? Meet a mom who claims her daughter died after getting the HPV vaccine, and hear all sides of the HPV vaccine controversy."
And indeed, reviews thus far show…
oracknows | December 4, 2013I'm not really happy to have to write this post, but a blogger's got to do what a blogger's got to do. The reason is that Katie Couric has done something requires—nay, demands—a heapin' helpin' of Orac's characteristic Respectful Insolence. Why should I give the proverbial rodent's posterior about who gets the Insolence today? The reason is that, when it comes to medicine, Katie Couric has done a fair amount of good. After the tragic death of her husband at a young age from colon cancer, she became an activist and spokesperson for colorectal cancer awareness, even famously undergoing her very…
oracknows | August 15, 2013Yet another zombie antivaccine meme rises from the grave to join its fellows
Oh, no, not again!
It was just two days ago that I decided to take on a zombie antivaccine meme that just keeps rising from the dead over and over and over again. I'm referring to the claim that Andrew Wakefield has been exonerated by legal rulings compensating children for alleged MMR-induced vaccine injury. As I pointed out, this particular claim is a steaming, stinking turd with no science (or even facts) behind it. As I further explained, even if a court rules that vaccines cause autism, that is not scientific…
oracknows | August 8, 2013Whenever I take a day off from blogging, as I did yesterday because I was too busy going out with my wife on Wednesday night to celebrate my birthday, I not infrequently find an embarrassment of riches to blog about the next day. Sometimes it's downright difficult to decide what to write about. So it was as I sat down last night to do a bit of blogging. I briefly considered writing about Suzanne Somers leaping into the fray to defend Stanislaw Burzynski, and maybe I still will. On the other hand, it's standard boilerplate Burzynski apologetics, not even very interesting; so maybe I won't.…
sa smith | June 3, 2013Michael Douglass recently announced that his battle with throat cancer was instigated by HPV.
We have known for a long time that males can benefit from the HPV vaccine series. I wrote this back in 2011:
CDC recommends HPV vaccine for boys!
It would be great, for women, if boys got the vaccine too. Of course, boys cannot get cervical cancer, but they can carry the virus and infect women and give them cervical cancer. Eliminated boys as carriers protects women. BUT…
We cannot, ethically, ask boys to get a vaccine that has risks with no/little benefit to themselves just to protect other people…
milhayser | April 25, 2013On ERV, Abbie Smith reports on the phenomenal success of the HPV vaccine in Australia. The vaccine, designed to protect against several types of sexually-transmitted papillomavirus, was first administered to Aussie girls in 2007. Since then, total prevalence of the virus among young women has dropped from 11.5% to less than 1%—and to 0% among girls who actually got the vaccine. These girls are also protecting their partners and reducing overall circulation of HPV; infections among young men, who were not even vaccinated, dropped from 12.1 to 2.2 percent. Abbie calls this a "blatant,…
aardvarchaeology | April 21, 2013As part of my duties as chairman of the Swedish Skeptics, earlier tonight I took part in a studio discussion on Swedish TV4 about Gardasil, the vaccine against human papilloma virus that is offered to all 12-y-o Swedish girls. It was a pretty silly affair. The TV people had decided on the angle that the information given about the vaccine to young girls isn't detailed enough. For instance, the school hallway fliers don't tell the kids that the protection rate against HPV isn't 100% (duh) or that very rarely the vaccine can provoke some serious side effects (duh again). These are traits, I…
sa smith | April 21, 2013The HPV vaccine works!
Genital warts in young Australians five years into national human papillomavirus vaccination programme: national surveillance data.
In Australia, they started vaccinating girls/women against HPV in 2007.
In 2007, 11.5% of women under 21 (age-range most likely to get the vaccine before they were sexually active) were diagnosed with genital warts.
0.85% in 2011.
0% in women under 21 who got the HPV vaccines.
0%.
For women 21-30 (only maybe got the vaccine, and even if they did, maybe after they were sexually active), it went from 11.3% to 3.1%.
For women over 30, there…
sa smith | March 27, 2013*throwsapaperdown*
Reasons for Not Vaccinating Adolescents: National Immunization Survey of Teens, 2008-2010
Our findings across 3 years show that, even as clinicians are increasingly recommending HPV, increasing numbers of parents, >40% in 2010, do not intend to vaccinate their adolescent female children with this vaccine. Parents intending to refuse are increasingly concerned about vaccine safety and seem less willing to accept clinician recommendations.
Yeah, what do us stupid virologists and immunologists and physicians know. Better just let your kid get a preventable disease that can…
sa smith | February 15, 2013This idea... this idea might be absolute genius...
Immunogenicity of bivalent human papillomavirus DNA vaccine using human endogenous retrovirus envelope-coated baculoviral vectors in mice and pigs.
The 'best' vaccines are live attenuated vaccines. Weakened/Misadapted viruses that can replicate a little bit, and get your immune system to generate a B-cell response (what you get with most vaccines) and a CTL response (what you really need a 'live' virus for).
But with some viruses, it isnt practical/possible to make an attenuated version (think HIV-1. aint nobody ever going to get an…