Skepticism/Critical Thinking
oracknows | June 16, 2013I never used to write much about genetically modified organisms (GMOs) before. I still don't do it that often. For whatever reason, it just hasn't been on my radar very much. That seems to be changing, however. It's not because I went seeking this issue out (although I must admit that I first became interested in genetic engineering when I was in junior high and read a TIME Magazine cover article about it back in the 1970s), but rather because in my reading I keep seeing it more and more in the context of anti-GMO activists using bad science and bad reasoning to justify a campaign to demonize…
oracknows | June 2, 2013Well, I've finally seen it, and it was even worse than I had feared. One might even say that watching it was like repeatedly smacking my head into a brick wall. It felt so good when it finally stopped.
I'm referring, of course, to Eric Merola's latest cinematic "effort. Ever since it was revealed that ric Merola's planned to make a sequel to his 2010 propaganda "documentary" about Stanislaw Burzynski, Burzynski The Movie: Cancer Is Serious Business, whose rank stupidity provided me with copious blogging material, I've finally actually seen the finished product, such as it is. Of course,…
oracknows | May 30, 2013Cancer is a bitch. Depending upon what organ is involved and what kind of cancer it is, it can be incredibly hard to cure. All too often, it is incurable, particularly when it involves the brain, pancreas, esophagus, or other organs. People wonder why, after over 40 years of a "war on cancer," we don't have better treatments and more cures. As I've explained before, it's because cancer is incredibly complex, and cancer cells have incredibly messed-up genomes. Even worse, cancer uses evolution against any efforts to treat it, producing such marked heterogeneity among tumor cells that not only…
oracknows | May 27, 2013I am taking the Memorial Day holiday off. I will return tomorrow. In the meantime, here's a general principle that needs to be remembered in cancer research:
I would also add to that list: So does bleach. So does acid. So does alkali. So does pouring the media out of the dish and letting the cells dry out. So does adding water to dilute the media. So do a variety of lethal poisons. So does heat. So does cold. The list goes on. Add to the list as you see fit!
The point, of course, is that it's very easy to kill cells in a cancer dish. What is difficult is selectively killing cancer cells in…
oracknows | May 15, 2013After yesterday, I really hadn't planned on writing about Angelina Jolie and her decision to undergo bilateral mastectomies again, except perhaps as a more serious piece next week on my not-so-super-secret other blog where The Name of the Doctor is revealed on a weekly basis. As I mentioned yesterday, there are a number of issues about the decision that could use my professional attention, from the process, to the evidence, to the issue of how the surgery was handled. Oh, and if I do decide to do that I'm sure I won't be able to resist a mention of some of the quackery that oozed out from…
oracknows | May 8, 2013A key pillar of the Stanislaw Burzynski antineoplaston marketing machine, a component of the marketing strategy without which his clinic would not be able to attract nearly as many desperate cancer patients to Houston for either his antineoplaston therapy (now under a temporary shutdown by the FDA that, if science were to reign, will become permanent) or his "personalized gene-targeted cancer therapy," which Burzynski represents as a discovery of his that large NCI-designated comprehensive cancer centers like M.D. Anderson or Memorial Sloan-Kettering are only now starting to copy, is the…
oracknows | May 6, 2013As hard as it might be to believe, one time over 20 years ago I actually took the Dale Carnegie course and, as part of that course, read his famous book How To Win Friends and Influence People. I know, I know. It's probably not obvious from my style of writing on this particular blog, but I did, and i tried to take the lessons to heart. The main reason I took the course, however, was because back then my public speaking truly sucked. I was nervous, hesitant, and tended to mumble a lot. That course was the first time I realized that I could be a halfway decent public speaker. Now, over 20…
oracknows | April 26, 2013A long, long time ago in a ScienceBlogs far, far away (well, it seems that way anyway, given the halcyon times back then before Pepsigate), Mark Hoofnagle coined the term "crank magnetism." It was a fantastic term used to describe how susceptibility to one form of quackery, pseudoscience, or just plain crankery tended to be associated with other forms of quackery, pseudoscience, or crankery. It explains why so many creationists tend to be into quackery and/or antivaccinationism, why so many 9/11 Truthers also tend to flirt with Holocaust denial or anthropogenic global warming denialists go…
oracknows | April 21, 2013Heidi Stevenson amuses me. I know, I know, I've started a previous post with exactly this sentence a mere month ago, but it's so damned appropriate that I can't help but try it again.
A homeopath (which means that she's reality-challenged to begin with), she's produced some of the most hilariously off-base, pseudoscientific, and downright antiscientific articles I've ever seen. Examples include the times when she launched a truly nonsensical attack on Stephen Barrett of Quackwatch, lectured scientists about anecdotal evidence, or, most hilariously of all, utterly misunderstood the concept of…
oracknows | April 19, 2013If there is one aspect of cranks that is almost universal (besides the aforementioned tendency to want to prove themselves through things like "live televised debates"), it's a tendency to want to shut down the criticism of its opposition. True, such a tendency is a human trait as well and used far too often by, say, corporations, but it's one that seems to be cranked up to 11 and beyond, as they say, in cranks.
We've seen it time and time again. Most often, it takes the form of some sort of legal bullying, such as when the British Chiropractic Association bit off more than it could chew by…
oracknows | April 5, 2013Over the years this blog's been in existence, I've fallen into a habit in which I tend to like to finish off the week taking on a bit of science (well, usually pseudoscience) that is either really out there, really funny, or in general not as heavy as, for example, writing about someone like Stanislaw Burzysnki. Indeed, for nearly two years, I even turned into a feature, Your Friday Dose of Woo. Eventually, I got a bit tired of being straitjacketed into having to find something kooky or wacky every Friday, and I let the feature lapse. That doesn't mean that I don't still deliver an occasional…
oracknows | April 3, 2013Every so often I come across a news story relevant to the subject matter usually encompassed by this blog that makes me shake my head in disbelief at the sheer stupidity. OK, every day, if you count the antivaccine movement and its attacks on papers like the one I wrote about Monday and yesterday. True, the constant barrage of pseudoscience, quackery, and generalized scientific ignorance that the antivaccine movement floods me with constantly threatens to drown out everything else, even from other areas of medicine. This one, however, caught my attention. It was about a joke done by two…
oracknows | March 28, 2013"Common sense" is not so common. Actually, that's not exactly right. What I meant was that what most people think of as "common sense" has little or nothing to do with what science concludes. Evidence talks, "common sense" walks. I saw a fantastic example to illustrate this point on a certain blog that I've found nearly as useful as a target topic to blog about as the antivaccine crank blog Age of Autism (AoA). I'm referring, of course, to The Thinking Moms' Revolution (TMR), an antivaccine crank blog almost as cranky as (and sometimes even more cranky than) AoA., and the post that drew my…
oracknows | March 27, 2013When I wrote about the Trial to Assess Chelation Therapy (TACT) trial last week, little did I suspect that I would be revisiting the topic again so soon. For those of you not familiar with TACT, it was a trial designed to test a favorite quack treatment for cardiovascular disease, chelation therapy. It is, as I have described many times in the past, an incredibly implausible therapy based on a hugely simplistic concept that because calcium accumulates in atherosclerotic lesions, then using chelation therapy could remove the calcium and reduce the lesions. Chelation therapy is a favorite…
oracknows | March 27, 2013It's been a while since I've written about Brian Berman. We first met him when he somehow managed to insinuate a "case report" of chronic low back pain into The New England Journal of Medicine in which he recommended acupuncture for this patient. Dr. Berman also happens to be a founder of quackademic medicine on par with Andrew Weil. True, he's not as famous to a lay audience as Weil is, but his influence on quackademic medicine over the last couple of decades has been enormous. It's not for nothing that David Freedman picked Berman as the main subject of his pro-"integrative medicine"…
oracknows | March 24, 2013There are many fallacies that undergird alternative medicine, which evolved into "complementary and alternative medicine" (CAM), and for which the preferred term among its advocates is now "integrative medicine," meant to imply the "best of both worlds." If I had to pick one fallacy that rules above all among proponents of CAM/IM, it would have to be either the naturalistic fallacy (i.e., that if it's natural—whatever that means—it must be better) or the fallacy of antiquity (i.e., that if it's really old, it must be better). Of course, the two fallacies are not unrelated. In the minds of CAM…
oracknows | March 12, 2013With very limited exceptions, chelation therapy is, as I said before in my somewhat Insolent opinion, is pure quackery. The sole exception is for real, documented cases of acute heavy metal poisoning that are known to respond to chelation, such as iron overload due to transfusion, aluminum overload due to hemodialysis, copper toxicity due to Wilson's disease, acute heavy metal toxicity, and a handful of other indications. Basically, chelation therapy involves infusing chemicals that can bind to metal ions and make them easier for the kidneys to excrete. The problem is, there is no good basic…
oracknows | March 8, 2013So I finally made it to the Society of Surgical Oncology Annual Symposium. Thanks to the snowstorm that apparently wasn't (at least, I don't see any snow around), my arrival was delayed by a day, as all flights to the Washington, DC area were canceled on Wednesday. But I did finally get here, and, although I missed most of the first day, I did at least get to see a talk given by a friend of mine late in the day and I had a chance to hang out for a while with an old friend.
I also got the chance after I got back to my hotel room to be highly amused by a "response" to criticism from the author…
oracknows | March 7, 2013I'm not a big fan of Cancer Treatment Centers of America (CTCA). That I don't much like CTCA should come as no surprise, given that this particular hospital chain distinguishes itself from other hospital chains by advertising its full body embrace of quackery, in particular "naturopathic oncology." At the same time as it's advertising its "integrative cancer care." It all sounds great on the surface, but anyone who understands exactly what "integrative medicine" is and how it basically represents the evolution of quackery will also understand that when you "integrate" quackery and…
oracknows | January 22, 2013Way back in the day, when I was a newbie at countering the mass of hysterical pseudoscience that is the antivaccine movement, particularly the myth that vaccines cause autism, a blogger by the 'nym of Prometheus taught me that autism and autism spectrum disorders (particularly by antivaccinationists and believers in the quackery known as "autism biomed") are conditions of developmental delay, not developmental stasis. Autistic children can and do exhibit improvement in their symptoms simply through growth and development. However, parents who subject their children to "autism biomed" quackery…