Various viruses

Thus far this week, I've discussed the history of pandemic influenza in general, and avian flu in particular. I've discussed some issues that must be addressed to prepare us for a pandemic, and the groundbreaking resurrection of the Spanish influenza virus. Today I want to end the series with a look at how prepared we currently are as a nation, and highlight some personal preparedness steps you can take. If you recall from Tuesday, the first outbreak of H5N1 was back in 1997. The anthrax attacks were in 2001. Surely by now we're prepared for some kind of serious, large-scale, biological…
I know I said I was going to discuss a bit more about pandemic preparedness today, but I think I'll hold off on that to discuss this story: It sounds like a sci-fi thriller. For the first time, scientists have made from scratch the Spanish flu virus that killed millions of people in 1918. Why? To help them understand how to better fend off a future global epidemic from the bird flu spreading in Southeast Asia. Researchers believe their work offers proof the 1918 flu originated in birds, and provides insights into how it attacked and multiplied in humans. On top of that, this marks the first…
The scientific community is all too familiar with the dangers an influenza pandemic could bring. The politicians and general public are starting to become aware of the issue as well; indeed, one can hardly open a newspaper or turn on the television without hearing about "bird flu." So, what's actually being done to prevent an influenza catastrophe? What are the issues? What can be done? These are the questions that keep public health officials awake at night, because the answer is always that we're not doing enough. While we may be resigned to the fact that a future pandemic can't be…
Anyone working in the area of influenza virus epidemiology is familiar with the name Robert Webster. A virologist at St. Jude's Children's Hospital in Memphis, the native New Zealander has been leading the charge against influenza for well over 40 years. Barely out of graduate school, Webster hypothesized that something like genetic reassortment (which had not yet been discovered) occurred to cause the big changes that appeared among human influenza viruses, driving pandemics. He performed a simple experiment that cemented the course of his career: he found that serum from patients who had…
It's hard to avoid hearing about influenza virus these days. In all the noise, it's tough to sort out the facts from the rumors and conspiracy theories. I've already discussed a bit about the basic biology of the virus in this post, so I'm not going to review that here (though a good overview can be found here for those of you who need to bone up on your influenza virus biology). So, this week, as a part of Pandemic influenza awareness week, I'll be writing a 5-part series about various issues regarding influenza. Today, I'll discuss the history of influenza, focusing on past pandemics. The…