Here is a link to an awesome animation (via Pure Pedantry). You have your membranes, actin and microtubule cytoskeleton, kinesin based vesicular transport, mRNA nuclear export, protein synthesis and coinsertional translocation into the ER, and membrane traffic from the Golgi to the plasma membrane. (Hey almost everything I've ever worked on!)
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Just a quick lab advertisement, my bay mate Yoko and my boss Tom have a review article in Cell about how morphological differences between various regions of the endoplasmic reticulum (ER) are representative of functional differences.
You can divide the ER into 3 morphological parts.
- The Nuclear…
OK this is an attempt to revive the blog. This entry is inspired by a talk given about a month ago by my mentor, Tom Rapoport. I hope that it will be the first of a series of posts where I ramble on about what we don't know. In each post I'll discuss a topic that remains mysterious. I'll try to…
I've written much about the Nuclear Pore Complex (NPC). This large molecular gate controls the flow of molecules into and out of the nucleus. Recent work (see this post and this new paper) describes how filaments containing "FG repeats" form a matrix in the center of the pore that blocks the…
In this day, some biologist have to move beyond the simplistic view that the cell is a bag of M&Ms. What do I mean by that? It's the idea that enzymes and organelles are free floating entities within the cell.
On the other hand, don't tell me that the cytoskeleton provides a static skeleton…
That cellular animation is quite impressive, Alex.
It's bloody impressive.
Doesn't get across the feel of the CHAOS and EXCITEMENT and how utterly, utterly crowded the cell is, but a compromise had to be made to get this point across.
I absolutely *adore* the kinesin, doggedly trudging up the µtubule. . .
A long time ago came a man on a track/Walking forty miles with a pack on his back/
He put down his load where he thought it was the best/And built a home in the wilderness. . .
nice site
http://www.aishwaryaraiworld.org/
here is a link to a better video version of the inner life of a cell
http://aimediaserver.com/studiodaily/videoplayer/?src=harvard/harvard.s…