thoughts of war...

the Hill of Megiddo.
Now, aren't you sorry you asked?

No, they wouldn't be heading to the middle-east. My guess would be Kandahar or Bagram air bases in Afghanistan for a possible mission into Iran if necessary. The choice of jet is interesting, though: The F-15 is an air-force jet, not a naval aircraft. Most of our airpower in the middle-east is largely naval (since we can park carriers in the Gulf and Med). The choice of 15s implies that they expect to be launching and landing in an airbase.

The 15E is also an odd bird, being an air superiority fighter retrofitted for bombing runs. The choice of 15Es over an F-117 implies that they're more concerned about having something more maneuverable to deal with air cover than they are about avoiding SAMs, and the choice of F-15Es over a more conventional mixed F-16 and F-15 force, or an F-22 and F-35 force implies that they want as small a force as possible, choosing a fighter/bomber hybrid over a mixed fighter and bomber squad.

Why?

Clearly the intent is to take out specific, known targets. The choice of smaller, more accurate bombs probably rules out a strike on Iran's nuclear program, though, since the facilities at Busehr and elsewhere are reportedly deep underground.

Israel/Lebanon makes even less sense, though, since there's nothing these jets would do there that couldn't be accomplished by an F-18 off a carrier.

Clearly they intend to attack from an airbase, against a country whose air defenses include an air force (rather than just SAMs like most Arab countries), with specific strategic targets, and get in and out as quickly as possible.

In the region you mention, only Iran makes sense as a target.

The choice of 15Es over an F-117 implies that they're more concerned about having something more maneuverable to deal with air cover than they are about avoiding SAMs

Other factors would influence this decision, such as payload and operational cost.