As always on Friday, there are new article published in the community journals - PLoS Pathogens, PLoS Computational Biology and PLoS Genetics. Here are few of my picks:
Growth of H5N1 Influenza A Viruses in the Upper Respiratory Tracts of Mice
Universally Sloppy Parameter Sensitivities in Systems Biology Models
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Every couple of months a major flu paper appears purporting to reveal why the 1918 H1N1 virus was so horrifically virulent in comparison to the other pandemic viruses of the last century, H2N2 (1957 pandemic) and H3N2 (1968 pandemic). It's not just the H1N1 subtype of the influenza A virus that…
So, let's see what's new in PLoS Genetics, PLoS Computational Biology, PLoS Pathogens and PLoS Neglected Tropical Diseases this week. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. Here are my own picks for the week - you go…
The headline was worrisome: "Bird flu becoming riskier for humans." The story was about a new paper in PLoS Pathogens from Kawaoka's lab that was said to identify "a specific change that could make bird flu grow in the upper respiratory tract of humans," according to the lab leader.
Birds usually…
Interesting paper from McAuley et al. (St. Jude's) on the PB1-F2 protein produced by an alternative reading frame on the PB1 gene of the influenza A virus. Most of you know that genes encode proteins via a three letter code. If you read the sequence of three letters by starting one letter earlier…