Prenatal Down syndrome tests are a go (at some point)

Last spring there was a false alarm about a noninvasive form of prenatal testing, in particular for Down syndrome. But if The Guardian is right then the British NHS is pushing forward on a more general program in this direction:

The early signs are so promising that the professor leading the programme says that the risk-free test could be the standard method of detecting babies with some genetic conditions inherited from the father within two to three years and those with Down's syndrome within five - and in the process save the lives of an estimated 265 mostly normal babies a year.

The life-saving part is that there would be far less need for amniocentesis, which is invasive and results in a risk of miscarriage. The cost vs. benefit of prenatal screening would presumably shift. Though British newspapers are inclined toward sensationalism and inaccuracy, this is probably grounded in something real.

H/T:

More like this

Today's NYT describes a new strategy for Down Syndrome screening. The new test, developed by a company called Sequenom, screens the mother's blood sample for fragments of RNA produced from fetal chromosomes. Dr. Lo looked for genes on Chromosome 21 that were active in the fetus but not in the…
There is a joke expression about surgeons, "sometimes wrong, never in doubt." Depending on how you feel about surgeons I've heard it begin "sometimes right" and "even when wrong." Applied to Rick Santorum, I think it has to be "usually wrong" if not "always wrong" given the serious of ridiculous…
One of the blogs I read regularly is Ben Goldacre's "Bad Science". I recommend it highly. (Which reminds me that I really need to find some time to update my blogroll!) In saturday's entry, he discussed a BBC Radio documentary that described how Britain is becoming a much more welcoming place for…
Screening for disease, especially cancer, is a real bitch. I was reminded of this by the publication of a study in BMJ the very day of the Science-Based Medicine Conference a week and a half ago. Unfortunately, between The Amaz!ng Meeting and other activities, I was too busy to give this study the…

The Guardian seems to have adopted the pro-lifer terminology, "unborn babies" instead of "fetuses."

The Guardian seems to have adopted the pro-lifer terminology, "unborn babies" instead of "fetuses."

why do you think that american terminologies would have any valence for british people?

Razib is right: for British people the two terms are interchangeable. Fetuses sounds more scientific, though, so I think it tends to get used less just because it sounds a bit awkward.

ah, I see they're using extracellular DNA(?). New development since I last looked at the field. Seems more efficient than the way they used to try to do it, straining the bloodstream for the tiny numbers of fetal cells.