razib | December 6, 2008Analysis of East Asia Genetic Substructure Using Genome-Wide SNP Arrays:
In this study, population differentiation (Fst) and Principal Components Analyses (PCA) are examined using >200 K genotypes from multiple populations of East Asian ancestry. The population groups included those from the Human Genome Diversity Panel [Cambodian, Yi, Daur, Mongolian, Lahu, Dai, Hezhen, Miaozu, Naxi, Oroqen, She, Tu, Tujia, Naxi, Xibo, and Yakut], HapMap [ Han Chinese (CHB) and Japanese (JPT)], and East Asian or East Asian American subjects of Vietnamese, Korean, Filipino and Chinese ancestry. Paired Fst…
razib | December 5, 2008Adaptive Complexity takes issue at a post over at Information Processing over race & genetics. On that specific topic, let me just quote Luigi Luca Cavalli-Sforza:
[my question] Question #3 hinted at the powerful social impact your work has had in reshaping how we view the natural history of our species. One of the most contentious issues of the 20th, and no doubt of the unfolding 21st century, is that of race. In 1972 Richard Lewontin offered his famous observation that 85% of the variation across human populations was within populations and 15% was between them. Regardless of whether…
razib | December 5, 2008The Genetic Legacy of Religious Diversity and Intolerance: Paternal Lineages of Christians, Jews, and Muslims in the Iberian Peninsula:
Most studies of European genetic diversity have focused on large-scale variation and interpretations based on events in prehistory, but migrations and invasions in historical times could also have had profound effects on the genetic landscape. The Iberian Peninsula provides a suitable region for examination of the demographic impact of such recent events, because its complex recent history has involved the long-term residence of two very different populations…
razib | December 3, 2008I've been doing some political blogging at the Secular Right site for about a week. I have to say that production is way easier when it comes to political blogging, but maintenance is way more exhausting.
razib | December 3, 2008The Etruscan timeline: a recent Anatolian connection:
The origin of the Etruscans (the present day Tuscany, Italy), one of the most enigmatic non-Indo-European civilizations, is under intense controversy. We found novel genetic evidences on the mitochondrial DNA (mtDNA) establishing a genetic link between Anatolia and the ancient Etruria. By way of complete mtDNA genome sequencing of a novel autochthonous Tuscan branch of haplogroup U7 (namely U7a2a), we have estimated an historical time frame for the arrival of Anatolian lineages to Tuscany ranging from 1.1 +/- 0.1 to 2.3 +/- 0.1 0.4 kya B.P…
razib | December 3, 2008Though Barbara Oakley's Evil Genes: Why Rome Fell, Hitler Rose, Enron Failed, and My Sister Stole My Mother's Boyfriend is ostensibly about Machiavellian behavior, it is also a testament to her intellectual ambition. The subheading is a clear pointer to this. Oakley attempts to synthesize a wide range of fields, behavior genetics, cognitive neuroscience, clinical psychology, diplomatic history, evolutionary psychology, economic history, along with heavy dollops of political and personal biography, to produce a portrait of how Machiavellian intelligence emerges from its biological substrate…
razib | December 2, 2008Romania removes theory of evolution from school curriculum:
Romania's withdrawal of the theory of evolution from the school curriculum could be evidence of a growing conservative tendency in teaching. Evolution has been removed from the school curriculum in a move which, pressure groups argue, distorts children's understanding of how the world came into being.
Meanwhile, religious studies classes continue to tell Romanian children that God made the world in seven days.
The theory of the Origin of Species and the evolution of humans is no longer present in the compulsory curriculum, through a…
razib | November 30, 2008A few years ago I blogged about prosopagnosia, "face blindness." Nature Neuroscience now has a new paper finding some correlates with brain architecture, Reduced structural connectivity in ventral visual cortex in congenital prosopagnosia:
Using diffusion tensor imaging and tractography, we found that a disruption in structural connectivity in ventral occipito-temporal cortex may be the neurobiological basis for the lifelong impairment in face recognition that is experienced by individuals who suffer from congenital prosopagnosia. Our findings suggest that white-matter fibers in ventral…
razib | November 30, 2008FuturePundit points me to a research paper, Impact of a new national screening policy for Down's syndrome in Denmark: population based cohort study:
Results The number of infants born with Down's syndrome decreased from 55-65 per year during 2000-4 to 31 in 2005 and 32 in 2006. The total number of chorionic villus samplings and amniocenteses carried out decreased from 7524 in 2000 to 3510 in 2006. The detection rate in the screened population in 2005 was 86% (95% confidence interval 79% to 92%) and in 2006 was 93% (87% to 97%). The corresponding false positive rates were 3.9% (3.7% to 4.1%)…
razib | November 30, 2008I was waiting for Dan MacArthur to comment on the "ACTN3 sports gene" story because I knew he had done research on this very locus. As usual, he's rather diplomatic, with a post titled The ACTN3 sports gene test: what can it really tell you?. He says:
Kevin Fischer has already noted that from a pure cost-benefit point of view the ATLAS test doesn't compete with the offerings of personal genomics companies. ATLAS will charge you $150 for testing ACTN3; for just $250 more, you get genetic information pertaining to more than 90 different conditions and traits from 23andMe. Neither test is…
razib | November 25, 2008If the title piques your interest, check out a new ScienceBlog of that name. The contributors are familiar faces....
razib | November 25, 2008Since the Right is roiling with faction, I thought I'd point you to a new weblog, Secular Right. No need to explain what it's about, the title says it all. John Derbyshire recounts an interesting experience at the H. L. Mencken Club:
Well, so there I was sitting down to dinner on the first evening of this Menckenfest. Seeing a plate of salad in front of me, I applied some condiments and started eating. In between the second and third mouthfuls I heard an amplified voice coming from the speakers' tables: "All right, everybody, we shall now say Grace. Bless us O Lord and these thy gifts…
razib | November 23, 2008An editorial in The New York Times, Bring Back the Woolly Mammoth?:
No one is quite sure why the woolly mammoths died out toward the end of the last ice age, some 10,000 years ago. Theories include warmer temperatures that gradually displaced the plants on which they fed, overhunting by primitive man, an accumulation of harmful genetic mutations, widespread disease, or an asteroid or comet colliding with Earth and disrupting the climate.
If scientists do bring back a few mammoths, we suspect our warming world won't look any more hospitable than the one that did them in.
A meta-point here is…
razib | November 22, 2008After reading American Colonies: The Settling of North America, I was struck by the incredible similarities in British modus operandi in North America and India the 17th and 18th centuries. These two imperial domains seem very different, but recall that Lord Cornwallis plays a prominent role in both Colonial and Indian history. This was a world-wide empire, the French and Indian War in North America was just a piece of the broader Seven Years' War, which also played out in India.
But aside from the broad-brush banalities of empire, it is notable the extent to which the early colonies used…
razib | November 21, 2008The Elf pointed me to Typealyzer where it supposedly analyzes the personality of the weblog. Well, this blog is....
...INTJ - The Scientists:
The long-range thinking and individualistic type. They are especially good at looking at almost anything and figuring out a way of improving it - often with a highly creative and imaginative touch. They are intellectually curious and daring, but might be pshysically hesitant to try new things.
The Scientists enjoy theoretical work that allows them to use their strong minds and bold creativity. Since they tend to be so abstract and theoretical in their…
razib | November 21, 2008In my post yesterday where I compared Catholics & Protestants in New England with Southerners in the McCain Belt, I was struck on the evolution question that in New England Protestants exhibited much more variance than Catholics. More Protestants rejected evolution or definitely believed it was true than Roman Catholics, who tended to agree that it was probably true. To me, this indicates the fissiparous tendencies of Protestantism, whereby new sects emerge from schisms within denominations, in contrast to the "broad church" philosophy of Roman Catholicism as well as the due deference…
razib | November 21, 2008Another paper on European phyogeography, Investigation of the fine structure of European populations with applications to disease association studies:
An investigation into fine-scale European population structure was carried out using high-density genetic variation on nearly 6000 individuals originating from across Europe. The individuals were collected as control samples and were genotyped with more than 300 000 SNPs in genome-wide association studies using the Illumina Infinium platform. A major East-West gradient from Russian (Moscow) samples to Spanish samples was identified as the first…
razib | November 21, 2008Gene Regulation in Primates Evolves under Tissue-Specific Selection Pressures:
Regulatory changes have long been hypothesized to play an important role in primate evolution. To identify adaptive regulatory changes in humans, we performed a genome-wide survey for genes in which regulation has likely evolved under natural selection. To do so, we used a multi-species microarray to measure gene expression levels in livers, kidneys, and hearts from six humans, chimpanzees, and rhesus macaques. This comparative gene expression data allowed us to identify a large number of genes, as well as specific…