Whenever we discuss vaccines and vaccine hesitancy, thanks to Andrew Wakefield the one vaccine that almost always comes up is the MMR, which is the combined measles-mumps-rubella vaccine. In 1998, Wakefield published a case series of cherry-picked patients in which he strongly inferred that the MMR vaccine was associated with autism and “autistic enterocolitis.” Of course, even the way Wakefield spun it, this wasn’t enough evidence to link the MMR vaccine to autism, which is no doubt why Wakefield never explicitly said that it did in the paper describing his case series. My guess has always…

There’s a class of studies that I sometimes refer to as “Well, duh!” studies because their conclusions are so mind-numbingly obvious that one wonders why anyone did the study in the first place. Sometimes that name is meant sarcastically, as in, “Why did these investigators waste the time, effort, and resources to do this study? No, really, why?” Sometimes, though, “Well, duh!” studies are useful and justified because they confirm a conclusion that everyone strongly suspected but for which there wasn’t direct evidence. So it was with a “Well, duh!” study that was published in the October…

Whenever I refer to quackademic medicine and how the infiltration of quackery into medical academia has led to unethical clinical that are not only pseudoscientific wastes of money but potentially downright harmful to patients, two always come to mind. The first is the trial that tested the late Nicholas Gonzalez’s protocol for advanced pancreatic cancer, comparing it to standard-of-care chemotherapy. His protocol basically involves a combination of supplements (up to 150 a day), various vegetable juices, and, yes, the infamous coffee enema—several a day, actually. It’s basically a mystical,…

I first became more interested in dubious stem cell clinics nearly two years ago, when I learned that hockey legend Gordie Howe was undergoing stem cell therapy in Mexico to treat his stroke. Being from Detroit, I imbibed the hockey madness of this town growing up, and know that Detroiters hold Gordie Howe in incredibly high esteem. Prominent in stories about Howe were two companies: Stemedica Cell Technologies, a San Diego company marketing stem cell treatments for all manner of ailments, and Novastem a partner company in Mexico that uses Stemedica products. Also prominent in the stories was…

I’ve referred to so-called “right to try” laws as a cruel sham.on more than one occasion. Since 2014, these laws, all based on a template provided by the libertarian Goldwater Institute, have been proliferating at the state level with the help of lobbying by the aforementioned Goldwater Institute and a concept that makes it pitifully easy to caricature opposition to these laws as wanting to heartlessly snatch away from terminally ill patients the last chance at life while laughing and twirling one’s mustache like Snidely Whiplash. Not surprisingly, state legislatures all over the country have…

One of the things that first led me to understand the dangers of quackademic medicine was a trial known as the Trial to Assess Chelation Therapy, or TACT. Chelation therapy, as you might recall, is the infusion of a chelating agent, or a chemical that binds heavy metals and makes it easier for the kidney to secrete them, in order to treat acute heavy metal poisoning. Unfortunately, quacks of all stripes have latched on to chelation therapy to treat a number of diseases and conditions. For instance, antivaccine quacks like to use chelation therapies to treat autistic children using the…

I’m sure that most of you watched the Presidential debate on Monday night, just as I did. Over the years, these debates have always always painful for me to watch, given the candidates’ tendency to answer the question they want to answer rather than the question actually answered; to find ways to spew prepackaged talking points into answers, whether they’re related to the question or not; and, above all, to see how much spin they can get away with. Particularly annoying is when they pander to their base with particularly brain dead bon mots. Candidates from both parties do it, of course, but…

It’s been nearly three weeks since we learned that the Medical Board of California had initiated disciplinary proceedings against the most famous antivaccine physician not named Andrew Wakefield. I’m referring, of course, to “Dr. Bob” Sears, author of The Vaccine Book: Making the Right Decision for Your Child and creator of an “alternate” vaccine schedule that “spreads out the vaccines.” Unfortunately, it’s a book that’s been very influential, in particular promoting the idea of “too many too soon” and claiming that delaying vaccines will reduce a child’s risk of autism. Basically, the…

One of the most effective spin techniques used by advocates of “integrative medicine” (also sometimes called “complementary and alternative medicine,” or CAM for short) to legitimize quackery has been to claim basically all non-pharmacologic, non-surgical interventions as “integrative,” “complementary,” or “alternative.” Thus, science-based interventions such as diet changes to treat and/or prevent disease, exercise, and other lifestyle alterations are portrayed as somehow so special, so outside the mainstream, that they need their own specialty, “integrative medicine,” even though they are…

If there’s one thing that irritates me more than government agencies making bold proclamations about making progress in cancer but not providing sufficient funding to have even a shot of realizing such ambitions (I’m talking to you, Cancer Moonshot), it’s people in other disciplines that are not cancer biology making bold proclamations about how they’re going to “solve” cancer or coming up with new “theories” to explain cancer. That’s not to say that cancer research can’t benefit from new perspectives from different sciences and disciplines can bring or new ways of thinking about the problem…

One of the most pernicious changes in medicine that’s occurred over the last 25 years or so is the infiltration of what I like to refer to as “quackademic medicine.” It’s a term that was, as far as I know, coined by Dr. Robert W. Donnell in 2009 to describe the infiltration of pseudoscience and quackery into medical schools and academic medical centers under the mantle of “complementary and alternative medicine” (CAM), now more commonly referred to as “integrative medicine. However, over the years, I’ve embraced the term to describe the “integration” of quackery and pseudoscience into…

I never in a million years thought I’d be writing a blog post involving Selena Gomez. Gomez, as many, if not most, of you are probably aware is currently a young pop star and actress who got her start as a child actress. Oddly enough, she was on Barney & Friends with Demi Lovato. These days, Gomez specializes in the variety of overproduced, lightweight pop that I don’t really listen to, although, ever since I subscribed to Apple Music, I’ve been known to listen to songs by performers like Selena Gomez and Demi Lovato just to see if I could figure out why they’re so popular. So far, I…

The Cancer Moonshot. It’s a topic that I’ve been meaning to address ever since President Barack Obama announced it in his State of the Union address this year and tasked Vice President Joe Biden to head up the initiative. Biden, you’ll recall, lost his son to a brain tumor . Yet here it is, eight months later, and somehow I still haven’t gotten around to it. The goal of the initiative is to “eliminate cancer as we know it,” and to that end, with $195 million invested immediately in new cancer activities at the National Institutes of Health and $755 million proposed for FY 2017. My first…

When I first heard that Donald Trump, the Republican nominee for President, was scheduled to appear on The Dr. Oz Show, my first thought was, basically, “Of course he is. What took him so long?” After all, it’s a crank pairing made in heaven. Given that, I considered it my skeptical blogging duty at least to watch the show, even if I never actually blogged about it. So I dutifully set my DVR to record it, and, after I got home from work, did my evening bike ride and ate dinner, I settled down in front of the television to see if this appearance would be as bad as I predicted in my mind. I’m…

As regular readers know, last Friday I was quite happy to relay the news that the Medical Board of California had finally acted against a rock star among the antivaccine movement, namely pediatrician “Dr. Bob” Sears. Dr. Sears (or Dr. Bob, as he likes to be called) rocketed to prominence among the vaccine-averse and downright antivaccine by writing a book called The Vaccine Book: Making the Right Decision for Your Child. It’s a book that Dr. Bob and his sycophants, toadies, and lackeys portray as being a “middle ground,” complete with an “alternative” vaccine schedule to the one recommended…

I didn’t think I’d be revisiting this topic again so soon, but damned if Alice Dreger didn’t write something that comes pretty close to demanding that I do so. I tried to resist, but unfortunately could not. Basically, I’m getting really, really tired of Dreger. Why do I say that? It’s because I’m having a harder and harder time not thinking that she has antivaccine proclivities. I don’t want to. I really don’t. But, damn, if she doesn’t keep sounding like a blogger on Age of Autism or The Thinking Moms’ Revolution. The echoes are unmistakeable and appeared again just yesterday. I first…

In the early days of this blog, I came up with a concept. That concept was based on the idea that on Friday I would try hard not to be so serious. On Fridays, I would seek out the finest woo in the world and aim a bit of my not-so-Respectful Insolence. Thus was born Your Friday Dose of Woo. It was a serious that I maintained close to religiously for nearly two years, before I started to feel the strain of having to com eup with something funny or quirky on every Friday. So gradually I let the series go, until it became an occasional feature. These days, it’s so occasional now that the last…

I’ve been critical of the National Center for Complementary and Integrative Health (NCCIH), which was until relatively recently known as the National Center for Complementary and Alternative Medicine (NCCAM) ever since I first discovered that it existed, lo, these many years ago. When I first discovered NCCIH, what struck me is how much pseudoscience it funded, including fellowships and educational programs in “complementary and alternative medicine” (CAM), which has rapidly morphed into “integrative medicine” (i.e., “integrating” quackery into real medicine). There were many NCCAM-funded…

After all the bad news that I’ve been blogging about, it’s a pleasure for me to end the week with a bit of very good news, very good news indeed. That news came in the form of an article published in the Orange County Register with the glorious title Dr. Bob Sears faces medical board discipline in recommendation not to vaccinate. Behold: Dr. Bob Sears, the Capistrano Beach pediatrician who is an outspoken critic of mandatory vaccination laws, faces possible state Medical Board discipline after he recommended that a 2-year-old patient forgo immunizations, according to legal documents made…

I’ve frequently called “right to try” laws that are popping up in various states like so much kudzu, to the point where 31 states have passed them in a little over two years, an amazing pace, a cruel sham, given how incredibly unlikely they are to help a single patient. Basically, state-level right-to-try laws are the brainchild of the libertarian Goldwater Institute and all based on a template that it produced. Their purpose is not, as the Goldwater Institute claims, to help patients, but rather to weaken and ultimately neuter the FDA’s power to regulate drug approval and thereby help to…