Methyltriphenoxy phosphonium iodide (Iodine time)

This reagent is one of my favorite ones for replacing an alcohol with an iodine.

i-40bad92267b21125b10a2354e60d0dac-methyltriphenoxyphosphoniumiodide.gif

Eric Kool's lab has made good use of it to iodinate the 5'-OH after automated synthesis of a DNA strand.

Tags

More like this