Triethylene Tetramine (Surprise, a polycation binds DNA)

A few months ago, a group published a report that this polyamine was an effective quadruplex ligand, inducing senescence of cancer cells.

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It's perhaps unsurprising that this works. I've previously covered Telomestatin (more selective) and TMPyP4 (less selective), but man, just a big charged chain of stuff? Apparently, though, this molecule is used in vivo already, in chelating copper ions in the treatment of Wilson's disease.

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fyi, the title and caption are different. I think the title should be 'triethylene ...'