Cyprodenate is an old antidote for benzodiazepene overdose:
It is a relatively rare drug that doesn't have a single aromatic ring - steroids are the broad class of exceptions that come to mind. It looks like this is some sort of cholinergic compound, but that's just an educated guess. Doesn't look like anyone uses it anymore, except some of the "smart drugs" crowd. Anyone know anything about it?
- Log in to post comments
More like this
I've always been reluctant to attribute antiscientific attitudes to one political persuasion or another--and justly so, or so I thought. While it's true that antiscience on the right is definitely more prominent these days, with the Republican candidates conducting virtual seminars on how to deny…
Once again, Big Pharma is under attack. Let me provide a different perspective.
Reporter Duff Wilson had some choice words in his characterization of this beleaguered industry:
They are all struggling with research failures as they scramble to replace their cash cows,...
Consumers should see a…
Ross Douthat is reputed to be a pretty smart guy. He blogged for the Atlantic before being given Bill Safire's old op-ed column at the New York Times. Safire, despite being wrong in may ways, was a sharp observer with good sources in DC, an analytical eye, and a sparkling intellect. Safire was…
I've got good news and bad news. I'll give you the good news first:
A cheap and simple drug that kills almost all cancers by switching off their "immortality". The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.…
Had to look this up, because I have never seen it used in hospital as a rescue drug. Apparently it is a stimulant - about as good as giving a drunk a cup of coffee.
Now we use flumazenil, a GABA antagonist, instead.
flumazenil is specifically a benzodiazepene antagonist, not a GABA agonist, right? The difference being that it only blocks GABA potentiation when a benzodiazepene is present...So theoretically it should have no effect in the absence of a benzo
oops...make that "...not a GABA antagonist..."
You can use Cyprodenate as a treatment in people who got intoxicated with antidepressives.
PV - I think you may be confusing cyprodenate with cyproheptadine. The latter drug has antihistaminergic and antiserotonergic effects and is sometimes used for the treatment of serotonin syndrome (eg. due to SSRI antidepressants).