depression gene

In case you missed them (or miss them, and want to read again ...) The (Illusory) Rise and Fall of the "Depression Gene" DIY circumcision with nail clippers Go figure. Oliver Sacks meets Jon Stewart Wheels come off psychiatric manual; APA blames road conditions Alarming climate change chart of the day Swine flu count in US hits 1 million; can't wait till flu season! Will government involvement drive up health-care costs? What if you could predict PTSD in combat troops? Oh, who cares...
Big psych news of the day is that a big JAMA study debunked the "depression gene" -- that is, this big new study (by Risch et alia, in JAMA, today) found that, contrary to a famous earlier big study (Caspi et alia, in Science, 2003), the short ("bad") form of a particular gene called 5-HTT does NOT make a person more vulnerable to depression. Or, to flip it:: Caspi 2003 had found that having a short version of 5-HTT, which affects processing of serotonin, put someone at more risk of depression if they experienced (as adults) repeated stressful life events. Risch 2009, crunching data from a…