neurobiology

Today's Weizmann Institute news stories include two new papers from the prolific lab of Prof. Yadin Dudai. The first is on a protein that boosts memory in rats. Dudai and his group have been investigating this protein for several years. Previously, they had managed to show that blocking the protein, even for a very short time, erases memories. Now, they have demonstrated that adding more of the protein to certain areas of the brain can strengthen memory. Note: They increased the protein via gene-carrying viruses that infiltrated the rats' brain cells - not a clinic-ready technique. But until…
Three news items were posted on our site today. The first is on two papers by a group in Spain. Normally we don't publicize papers that are not written by Institute scientists, but these are a special case. They appear to have clinched the claims of a Weizmann scientist that one can treat stroke and head trauma without trying to get drugs into the brain. The treatment would consist of upping the levels of a naturally-occurring enzyme in the blood; one of these papers showed that levels of this enzyme in the blood tests of stroke patients were the best predictor of their chances of recovery.…
Did Israeli singer-songwriter Arik Einstein know something that scientists didn't when he released the song "When You Cry You're Not So Pretty" back in 1969? Prof. Noam Sobel and his team of the Weizmann Institute of Science have now shown that merely sniffing a woman's tears - even when the crying woman is not present - reduces sexual arousal in men. This study raises many interesting questions. What is the chemical involved? Do different kinds of emotional situations send different tear-encoded signals? Are women's tears different from, say, men's tears? Children's tears? This study…
Morphological variation is important, it's interesting…and it's also common. It's one of my major scientific interests — I'm actually beginning a new research project this spring with a student and I doing some pilot experiments to evaluate variation in wild populations here in western Minnesota, so I'm even putting my research time where my mouth is in this case. There has been some wonderful prior work in this area: I'll just mention a paper by Shubin, Wake, and Crawford from 1995 that examined limb skeletal morphology in a population of newts, and found notable variation in the wrist…
The journal Nature has selected optogenetics as its "Method of the Year", and it certainly is cool. But what really impressed me is this video, which explains the technique. It doesn't talk down to the viewer, it doesn't overhype, it doesn't rely on telling you how it will cure cancer (it doesn't), it just explains and shows how you can use light pulses to trigger changes in electrical activity in cells. Well done!
A team of neuroscientists has made the coolest nerd porn film ever. They gave 16 women vibrators and asked them to bring themselves to orgasm while they made a movie…of their brains, using an MRI scanner. It's going to premiere at the Society for Neuroscience meetings. While it sounds like they have some interesting results — there is a consistent, wide-spread pattern of brain activity during orgasm, and specific areas are known to fire up — the article is not going to do a lot for Professor Barry Komisaruk's reputation. The interviewer asked a few too many trivial questions. "In women,…
Everyone should read this very good, very clear article in Seed magazine. It stomps on the concept of a soul from the perspective of modern neuroscience. The evidence supports another view: Our brains create an illusion of unity and control where there really isn't any. Within the wide range of works arranged along the axis of soulism, from Life After Death: The Evidence, by Dinesh D'Souza, to Absence of Mind, by Marilynne Robinson, it is clear there is very little understanding of the brain. In fact, to advance their ideas, these authors have to be almost completely unaware of neurology and…
It looks like I have to add another book to my currently neglected reading list. In an interview, Cordelia Fine, author of a new book, Delusions of Gender: How Our Minds, Society, and Neurosexism Create Difference(amzn/b&n/abe/pwll), has a few provocative things to say about gender stereotypes and the flimsy neuroscience used to justify them. So women aren't really more receptive than men to other people's emotions? There is a very common social perception that women are better at understanding other people's thoughts and feelings. When you look at one of the most realistic tests of…
There he goes again, making up nonsense and making ridiculous claims that have no relationship to reality. Ray Kurzweil must be able to spin out a good line of bafflegab, because he seems to have the tech media convinced that he's a genius, when he's actually just another Deepak Chopra for the computer science cognoscenti. His latest claim is that we'll be able to reverse engineer the human brain within a decade. By reverse engineer, he means that we'll be able to write software that simulates all the functions of the human brain. He's not just speculating optimistically, though: he's…
Even severely paralyzed people on respirators can do it: They can sniff. That is, they can at least partially control the movement of air through their nostrils. And if they can sniff, they can use this action to write on a computer screen or steer a wheelchair. That's the principle behind a new device developed by Prof. Noam Sobel, students and electronics engineers in the Weizmann Institute's Neurobiology Department. After teaching healthy volunteers to play computer games using a "sniff control" in lieu of a mouse or joystick, the Weizmann team entered into collaboration with Dr Nachum…
Anne Dillard said "You can't test courage cautiously," but Institute scientists have found a way to test it fairly safely, at least. One might think of courage as an abstract idea, but it turns out that acts of bravery reveal a unique activity pattern in the brain. An experiment at the Institute to identify the brain mechanisms that take control when the call to action conquers fear involved a live snake on a remote-controlled trolley and volunteers with a fear of snakes in an fMRI.
Years ago, when the Trophy Wife™ was a psychology grad student, she participated in research on what babies think. It was interesting stuff because it was methodologically tricky — they can't talk, they barely respond in comprehensible way to the world, but as it turns out you can get surprisingly consistent, robust results from techniques like tracking their gaze, observing how long they stare at something, or even the rate at which they suck on a pacifier (Maggie, on The Simpsons, is known to communicate quite a bit with simple pauses in sucking.) There is a fascinating article in the NY…
tags: Science CAN Answer Moral Questions, philosophy, morality, ethics, behavior, brain, neurobiology, religion, culture, well-being, human rights, human values, Sam Harris, TEDTalks, streaming video Questions of good and evil, right and wrong are commonly thought unanswerable by science. But Sam Harris argues that science can -- and should -- be an authority on moral issues, shaping human values and setting out what constitutes a good life. Adored by secularists, feared by the pious, Sam Harris' best-selling books argue that religion is ruinous and, worse, stupid -- and that questioning…
It's a little disturbing to see an entire vast field of science reduced to a one-page cartoon, but it did win an award for science visualization, and we've got to get people hooked on the cool stuff somehow.
tags: neurobiology, The Neurons that Shaped Civilization, mirror neurons, Ghandi neurons, social behavior, Lamarkian evolution, Darwinian evolution, VS Ramachandran, TEDTalks, streaming video Neuroscientist Vilayanur Ramachandran outlines the fascinating functions of mirror neurons. Only recently discovered, these neurons allow us to learn complex social behaviors, some of which formed the foundations of human civilization as we know it. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of…
On Thursday, I gave a talk at the University of Minnesota at the request of the CASH group on a rather broad subject: evolution and development of the nervous system. That's a rather big umbrella, and I had to narrow it down a lot. I say, a lot. The details of this subject are voluminous and complex, and this was a lecture to a general audience, so I couldn't even assume a basic science background. So I had to think a bit. I started the process of working up this talk by asking a basic question: how did something as complex as the nervous system form? That's actually not a difficult problem…
I'm going to be opening my mouth again on Thursday in Minneapolis — I'll be giving a talk in MCB 3-120 on the Minneapolis campus at 7:30 on Thursday, 3 December. This will be open to the public, and it will also be an all-science talk, geared for a general audience. I'd say they were going to check your nerd credentials at the door, but just showing up means you're already fully qualified. The subject of the talk is my 3 big interests: a) evolution, or how we got here over multiple generations, b) development, or how we got here in a single generation, and c) the nervous system, the most…
Here's part of an explanation I've liked for a long time: they're a product of developing cognitive processes that bias the brain to model the world with supernatural shortcuts. (Moved below the fold because the silly video defaults to autoplay.)
tags: technology, neurobiology, brain, Three ways the Brain Creates Meaning, Tom Wujec, streaming video Information designer Tom Wujec talks through three areas of the brain that help us understand words, images, feelings, connections. In this short talk from TEDU, he asks: How can we best engage our brains to help us better understand big ideas? [6:26] Take Home message: Creating technology that works intuitively with the way our brains function enhances our ability to solve really complex problems more efficiently. TEDTalks is a daily video podcast of the best talks and performances…
Chalfie is interested in sensory mechanotransduction—how are mechanical deformations of cells converted into chemical and electrical signals. Examples are touch, hearing, balance, and proprioception, and (hooray!) he references development: sidedness in mammals is defined by mechanical forces in early development. He studies this problem in C. elegans, in which 6 of 302 nerve cells detect touch. It's easy to screen for mutants in touch pathways just by tickling animals and seeing if they move away. They've identified various genes, in particular a protein that's involved in transducing touch…