vaccines

In a post the other day on some kind of flu vaccine mishap in Austria we called it a colossal screw-up. It turns out we may have understated the case. Maybe. Because while more details are leaking out, the company responsible for it, Baxter International, isn't saying exactly what happened on the grounds that it is confidential business information. You almost have to admire that kind of arrogance. Almost. Meanwhile Helen Branswell brings us more details: The company that released contaminated flu virus material from a plant in Austria confirmed Friday that the experimental product contained…
Busted! All right, I give up. Since I've been sucked into the whole vaccine thing again after only one day away, I might as well highlight this simultaneously amusing and depressing tidbit. Earlier today, I wrote about a coordinated attack by the antivaccine movement on the Autism Omnibus decision two weeks ago. Given that it involved Generation Rescue, Jim Carrey, Jenny McCarthy, Robert F. Kennedy, Jr., Deirdre Imus and her eirdre Imus Environmental Center for Pediatric Oncology, the Huffington Post, Age of Autism, and various other antivaccine activists, I thought it pretty obvious that…
As I write this the story is still hazy [see Addendum] but it sounds like the kind of colossal screw-up we had four years ago when the American College of Pathology sent a pandemic flu strain (H2N2) to thousands of clinical and hospital laboratories as part of routine competency testing (see here, here, here). That was inattention by CDC, whose Director was mesmerized by the bioterrorism phantom and couldn't see beyond them. This time it's a vaccine maker and the cock-up sounds pretty horrendous, although it is hard to figure out exactly what has happened given the incomplete descriptions and…
A just released report on world wide vaccine production capacity says . . . if you don't have access to the report (and I don't, as yet), what it says depends on which news source you want to read. For example you can read Reuters (the glass half full wire service stroy) or Agence France Presse (the glass half empty wire service study). Here are the ledes in each: Reuters: Drug companies have increased their capacity to make bird flu vaccines by 300% in the past two years but will still need four years to meet global demand in the event of a pandemic, a study says. It also said doses of…
I'm not sure what to make of the report that scientists in Boston, California and the CDC in Atlanta have made monoclonal antibodies that protect mice against many different flu subtypes. Monoclonal antibodies are antibodies made by the descendants of a single immune cell (that is a single clone, hence monoclonal). Thus unlike natural antibodies, these are also monospecific, i.e., they are directed against one specific target. Our natural immune system "sees" a protein on the surface of the virus called hemagglutinin (HA), of which there are 16 broad subtypes and many, many variations within…
Alright, I know that, after yesterday's epic post (which was long even by Orac-ian standards), I said that I was going to try to get away from vaccine blogging for a while. I lied. Well, not really. At that time I really did mean it. But then I came across something that I just couldn't leave alone. Regular readers of this blog know my opinion of Andrew Wakefield, namely that he is a fraud, a quack, a charlatan, and a danger to the health of autistic children and public health in general. There is, as documented in my post and elsewhere, abundant evidence to support my opinion. But apparently…
One thing that's become apparent to me so far in 2009 is that, while 2008 was the year of the antivaccinationist, 2009 is already shaping up to be a very bad year for antivaccinationists. A very bad year indeed, and this is a very, very good thing--if it can be sustained. But first, let's take a look at last year. In 2008, Jenny McCarthy was the new and fresh celebrity face of the movement that believes that autism and all manner of other neurodevelopmental disorders are caused by vaccines and that the government and big pharma are suppressing The Truth. She had emerged in the fall of 2007…
I knew it. I just knew it. I just knew that when I finally decided to come back from my absence from this blog that something very unpleasant and sad would be waiting for me. True, there had actually been one very nasty thing that I simply had to deal with a few days ago, but that was a particularly vile and despicable human being who, believe it or not, was not John Best. That is not the case here, although the misinformation being pushed is truly disturbing. Not surprisingly, what awaited me upon my decision to come back was posted earlier this week on that repository of antivaccine…
It seems the same questions keep coming up when looking at the cult leaders of the infectious disease promotion movement. When you listen to them preach or read their liturgy you can't help thinking, "dumb, evil, or both?" I think I'm going to vote for "both" when it comes to Deirdre Imus. Her sermon last week in the Huffington Post was so far over the top that my nose is still bleeding from climbing her tower of intellectual excrement. Her title advises health consumers, "On Vaccinations: Consider the Source and Follow the Money." I don't know what that means, but Deirdre explains, "…
Unfortunately, as we have been dreading for the last four months or so since her relapse was diagnosed, my mother-in-law passed away from breast cancer in hospice. She died peacefully, with my wife and the rest of her family at her side. As you might expect, I do not much feel like blogging. Because I foresaw this day coming, however, I did set up a series of "Best of" reposts to autopost for you while I am in mourning. Some I have even updated and/or spiffed up with actual editing. If you've been reading less than a year or two, they're new to you. If not, I hope you enjoy them again. I don'…
Last night, I lambasted Countdown host Keith Olbermann for having been played by the antivaccine movement and having unjustly slimed British journalist Brian Deer. Clearly, Olbermann was so blinded by his hatred of Rupert Murdoch that all chief apologist for the antivaccine movement, former freelance journalist David Kirby, had to do was mention that The Times of London, the newspaper that published Brian Deer's excellent investigative report nailing anti-MMR guru Andrew Wakefield to the wall for falsifying data, is owned by Rupert Murdoch, and it was like waving the proverbial red cape in…
My sciblings at Scienceblogs have done a pretty thorough fisking of the Andrew Wakefield affair.To recap breifly, a paper by Wakefield and others in The Lancet in 1998 raised an alarm that the widely used measles-mumps-rubella (MMR) vaccine was the cause of some cases of childhood autism and a chronic inflammatory bowel disease. The incriminated agent was alleged to be measles virus contained in the vaccine (MMR has never contained mercury preservative). The impact was dramatic and this issue became a powerful engine propelling the anti-vaccine movement. The result has been a real public…
Stick a fork in Keith Olbermann. He's done. He has now officially degenerated into a liberal version of Rush Limbaugh, except that Rush Limbaugh is occasionally funny. Maybe he's more like Sean Hannity, particularly in his apparent dedication to the truth, or, rather, lack thereof. Hannity detests liberals and will immediately attack on the slightest pretense, even if the information given to him of "liberal wrongdoing" is dubious or outright wrong. Like Hannity, Olbermann will never turn down an opportunity to attack Bill O'Reilly or his paymaster Rupert Murdoch. Somtimes it's justified, but…
I'm not as big a fan of Keith Olbermann as I used to be. Indeed, sometimes he strikes me as the liberal version of Rush Limbaugh, not to mention a blowhard. However, occasionally, he still has it, and when he's on, no one skewers the dishonest better than he does. For instance, after a media flack and the usual inclusion of Bill O'Reilly as runners up, meet Andrew Wakefield, the Worst Person in the World for February 10, 2009: */ Visit msnbc.com for Breaking News, World News, and News about the Economy That about sums it up right now. I wonder how long before the antivaccinationist loons…
Poor Jeni Barnett. You remember Jeni Barnett, don't you? She's the U.K. radio host whose ill-informed rants against vaccines Ben Goldacre exposed so gloriously last week. Unfortunately, the price Ben paid consisted of threats of legal action for "copyright infringement" in the form of his having posted audio of the relevant segment of Barnett's show. Yes, LBC, the radio station on which Barnett's show runs, threatened to sue, forcing Ben to take down the audio. However, as almost always happens when a blogger is threatened in such a manner, the specter of legal action led to the audio files…
I have to admit I'm somewhat surprised (even if Orac isn't). We all knew that Andrew Wakefield's research was bogus and the link between vaccines and autism was engineered by ideologues who fear vaccines irrationally. But fabrication of data? Sloppy research is one thing, but the need for cranks to be correct, no matter what reality reflects, has resulted in yet another example of egregious dishonesty. This is in line, however, with what we know about cranks. Mark Crislip recently wrote an interesting piece on mathematics crankery which bears upon just this phenomenon. Mathematics is a…
Because of the fallout from the revelation by Brian Deer that very likely Andrew Wakefield, hero of the antivaccine movement but, alas for his worshipers, one of the most dishonest and incompetent scientists who ever lived, had almost certainly falsified data for his infamous 1998 Lancet paper that launched a decade-long anti-MMR hysteria that shows no signs of abating, I ended up not coming back to a story I was very interested in. Although this story is about Holocaust denial, the questions raised by it are applicable not only to history and Holocaust denial, but to any area of science or…
Not again. I have no way of knowing if the media in my hometown happen to be more credulous when it comes to pseudoscience than average, but, given the number of stories referred to me emanating from Detroit and its surrounding suburbs, you'll forgive me if I'm very depressed right now. For instance, we have "investigative reporter" Steve Wilson of WXYZ Channel 7 Action News, who, although claiming the title of "Chief Investigator" for that station, clearly couldn't investigate his way out of a paper bag--at least when it comes to medical stories--given that he is known for routinely…
Last fall, I wrote about a new research paper which tried to replicate some of Andrew Wakefield's original results, which not only claimed a correlation between MMR vaccination and autism, but also the presence of measles virus in intestinal tissue. Wakefield had suggested that an inappropriate response to the presence of measles virus in this tissue may trigger conditions such as bowel disease and autism. The more recent study was unable to replicate any of Wakefield's findings--not surprising, since so many papers in the last decade have found no connection between vaccination and autism…
The Questionable Authority (apt name for this one!) ponders a disturbing report from the Times of London.